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  • Articles: DFG German National Licenses  (2)
  • Caffeine  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Effects of moderate exercise on the pharmacokinetics of caffeine (1991)
    Springer
    European journal of clinical pharmacology 40 (1991), S. 279-282 
    Details
    ISSN: 1432-1041
    Keywords: Caffeine ; Exercise ; Pharmacokinetics ; heavy coffe intake
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The effect of moderate exercise on the kinetics of caffeine in 12 healthy volunteers-6 heavy coffee drinkers (HD) and 6 light coffee drinkers (LD) has been studied. Kinetics at Rest was measured first (R): the subjects remained at rest for 8 h after a single 250 mg dose of caffeine. One week later, the Exercise Kinetics (E) was measured under the same conditions, but with the subjects performing moderate exercise (30% of VO 2 max) during the first hour of the study. Exercise raised the maximal plasma caffeine concentrations (R: 7.28; E: 10.45) and reduced both the half-life (R 3.99 h; E 2.29 h) and the volume of distribution (R 371; E 20.91). Both during exercise and at rest, HD had a greater half-life elimination and volume of distribution than LD. The results suggest potentiation of the effects of caffeine during exercise and an increase in its distribution due to regular heavy coffee intake.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00315209
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Caffeine increases maximal anaerobic power and blood lactate concentration (1992)
    Springer
    European journal of applied physiology 65 (1992), S. 188-191 
    Details
    ISSN: 1439-6327
    Keywords: Force-velocity exercise test ; Maximal anaerobic power ; Caffeine ; Lactate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The aim of this study was to specify the effects of caffeine on maximal anaerobic power (W max). A group of 14 subjects ingested caffeine (250 mg) or placebo in random double-blind order. TheW max was determined using a force-velocity exercise test. In addition, we measured blood lactate concentration for each load at the end of pedalling and after 5 min of recovery. We observed that caffeine increasedW max [964 (SEM 65.77) W with caffeine vs 903.7 (SEM 52.62) W with placebo;P〈0.02] and blood lactate concentration both at the end of pedalling [8.36 (SEM 0.95) mmol · l−1 with caffeine vs 7.17 (SEM 0.53) mmol · l−1 with placebo;P〈0.011 and after 5 min of recovery [10.23 (SEM 0.97) mmol · l−1 with caffeine vs 8.35 (SEM 0.66) mmol · l−1 with placebo;P〈0.04]. The quotient lactate concentration/power (mmol · l−1 · W−1) also increased with caffeine at the end of pedalling [7.6 · 10−3 (SEM 3.82 · 10−5) vs 6.85 · 10−3 (SEM 3.01 · 10−5);P〈0.01] and after 5 min of recovery [9.82·10−3 (SEM 4.28 · 10−5) vs 8.84 · 10−3 (SEM 3.58 · 10−5);P〈0.02]. We concluded that caffeine increased bothW max and blood lactate concentration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00705079
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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