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  • Articles: DFG German National Licenses  (2)
  • Chemistry  (1)
  • E-C coupling  (1)
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  • Articles: DFG German National Licenses  (2)
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  • 1
    ISSN: 1420-9071
    Keywords: Frog skeletal single fibres ; phenylglyoxal (PGO) ; E-C coupling ; solubilization ; PGO-binding protein (PGO-protein) ; monoclonal antibody ; electrometrin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The excitation-contraction (E-C) coupling process in single twitch fibres from frog toe muscle was inhibited selectively by phenylglyoxal (PGO), a specific guanidyl modifying reagent. A new protein (31.5 kDa), which has PGO-binding ability and seems to play a key role in the E-C coupling process, was solubilized from transverse tubule membrane-junctional sarcoplasmic reticulum complexes (TTM-JSR) of frog skeletal muscles, using14C-PGO. The monoclonal antibody against this protein applied extracellularly inhibited the E-C coupling process of the single fibres. This protein appears to constitute the very first step of input for E-C coupling. It is considered to behave as an indispensable part of an ‘electrometer’ to measure membrane potentials. Therefore, the name ‘electrometrin’ is suggested for the new protein.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 19 (1973), S. 975-981 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Monte Carlo techniques have been used to simulate the stochastic responses of the nonisothermal packed bed reactor. Random variables with specified ensemble means, ensemble standard deviations, and probability distributions (normal, uniform, or autocorrelated) were introduced as inputs and parameters into the model equations, and the equations were solved repeatedly to provide a sample of the outputs. Sample means and sample standard deviations both in the steady and unsteady state were evaluated and the probability distributions of the output temperature and concentration characterized. Confidence limits for a specified confidence coefficient have been determined from which overdesign factors could be computed.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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