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  • Articles: DFG German National Licenses  (3)
  • Corsi-Block test  (1)
  • Finite-element-method  (1)
  • Singlephoton emission tomography  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Short-term memory: no evidence of effect of rapid-repetitive transcranial magnetic stimulation in healthy individuals (1993)
    Springer
    Journal of neurology 240 (1993), S. 373-376 
    Details
    ISSN: 1432-1459
    Keywords: Transcranial magnetic stimulation ; Short-term memory ; Corsi-Block test ; Digit-Span test
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effect of rapid-repetitive transcranial magnetic stimulation (rr-TMS) on the immediate verbal and visuospatial memory span was assessed by computerized neuropsychological testing in 11 healthy volunteers. The objective was to test whether rr-TMS may be utilized as a non-invasive tool for evaluation of memory function. The subjects had to memorize series of numbers (Digit-Span test) or the position of cubes (Corsi-Block test) shown to them on a computer screen and actively reproduce them immediately after the presentation. Synchronous with the appearance of each item an rr-TMS train of 550 ms duration was delivered to the left or right anterolateral parietal as well as superior and posterior lateral temporal region at 50 Hz and with approximately 1.0 T stimulation intensity. Statistical comparison of memory performance during rr-TMS and baseline testings without stimulation revealed no significant changes. No adverse effects were observed. Thus, rr-TMS does not affect short-term memory performance in healthy individuals under the stimulation conditions described above.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00839970
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Brain single-photon emission tomography using technetium-99m bicisate (ECD) in a case of complex partial seizure (1994)
    Springer
    European journal of nuclear medicine 21 (1994), S. 1243-1246 
    Details
    ISSN: 1619-7089
    Keywords: Regional cerebral blood flow ; Singlephoton emission tomography ; Technetium-99m bicisate ; Epilepsy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The clinical application of technetium-99m bicisate (ethyl cysteinate dimer, ECD) for ictal and interictal studies of regional cerebral blood flow (rCBF) in a patient suffering from medically intractable simple and complex partial seizures is reported. The interictal study was performed 60 min p.i. and the ictal studies were performed at 60 min p.i. using an annular crystal single-photon emission tomography (SPET) system dedicated for high-resolution brain SPET imaging. Visual evaluation of the studies was carried out, as well as semiquantitative measurement of regional tracer uptake. Magnetic resonance imaging (MRI) scans revealed atrophy of almost the complete left frontal lobe and the ventral parts of the left temporal lobe, including in part the temporomesial structures. The left parietal and occipital structures and the right hemisphere were normal. The interictal study showed a large perfusion defect involving the whole left frontal lobe as well as the left temporal lobe with remaining small areas of normal cortical tracer uptake. The ictal studies detected circumscribed hyperperfusion within the left mesial temporal lobe (ventral part of the hippocampus). Additionally an increase in perfusion could be seen within the entire remaining left temporal lobe. Semiquantitative evaluation of tracer uptake comparing both studies detected markedly increased uptake within the focus compared to the remaining left temporal lobe. On this basis the newly available tracer for studies of rCBF, 99mTc-bicisate, seems to be of value for the detection of epileptogenic foci. Additionally, the value of ictal rCBF studies in the presurgical evaluation of those patients presenting severe morphological alterations on MRI is clearly underlined by this case.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00182361
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Properties of Advanced Headmodelling and Source Reconstruction for the Localization of Epileptiform Activity (1998)
    Springer
    Brain topography 10 (1998), S. 283-290 
    Details
    ISSN: 1573-6792
    Keywords: Source localization ; Current density reconstruction ; Boundary-element-method ; Finite-element-method ; Temporal lobe epilepsy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract During the last decade multiple work has been done to determine the sources of epileptiform activity by means of dipole source localization based on recordings of the magnetoencephalogram (MEG) or the electroencephalogram (EEG). The actual available advanced volume conductor models and the multiple source reconstruction by regularization may give new impulse to EEG based source analyses in epilepsy patients. This study demonstrates the principal properties of these techniques. We applied two different EEG source reconstruction techniques within different volume conductor models to localize induced spike activity in a selected patient suffering from medically intractable temporal lobe epilepsy: 1) single moving dipole solution in a 3-shell spherical model versus individual head models (boundary-element-model, BEM, and finite-element-model, FEM); 2) a regularization technique for current density reconstructions using both BEM and FEM. When compared to findings of invasive recordings no adequate source locations were derived from the moving dipole solution in both the 3-shell head model and BEM. In contrast, a high congruence of source reconstruction and invasive determination of the focus was obtained using the regularization techniques in both BEM and FEM, indicating the high spatial accuracy of this technique in individual head models.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1022275024069
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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