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  • Articles: DFG German National Licenses  (4)
  • Diagnosis  (2)
  • Endobrachyoesophagus  (2)
  • 1
    Electronic Resource
    Electronic Resource
    pH monitoring: The gold standard in detection of gastrointestinal reflux disease? (1993)
    Springer
    Dysphagia 8 (1993), S. 118-121 
    Details
    ISSN: 1432-0460
    Keywords: Gastroesophageal reflux disease ; Diagnosis ; pH monitoring ; Diagnostic studies ; Deglutition ; Deglutition disorders
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Gastroesophageal reflux disease (GERD) is one of the most frequent benign diseases of the gastrointestinal tract and in some cases the diagnosis may be very difficult. There are many diagnostic procedures but none of them could prove or definitely exclude the disease. The 24-h pH-monitoring is the “gold standard” for detection of gastroesophageal reflux and in many patients the reflux correlates with the GERD. The evaluation of a diagnostic method has to be done in a similar manner to the evaluation of therapeutic study (phase 1 to phase 4). For the definition of the “gold standard” for detection of a special diagnosis (e.g., the gastroesophageal reflux disease), the results of phase 3 studies for different methods had to be compared. The method with the best values for sensitivity and specificity is yet to be discovered. Until now, pH monitoring has been the gold standard for the diagnosis of GERD. However, there are many problems connected with using this method in clinical practice.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02266991
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Klassifikation der neuroendokrinen Tumoren des Gastrointestinaltrakts und des Pankreas und ihre therapeutische Relevanz (1997)
    Springer
    Der Chirurg 68 (1997), S. 107-115 
    Details
    ISSN: 1433-0385
    Keywords: Key words: Neuroendocrine tumor ; Carcinoid ; Diagnosis ; Therapy ; Gastrointestinal tract. ; Schlüsselwörter: Neuroendokriner Tumor ; Carcinoid ; Therapie ; Diagnostik ; Gastrointestinaltrakt.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung. In der vorliegenden Arbeit wird unter Einbeziehung der aktuellen Klassifikation der neuroendokrinen Tumoren des Gastrointestinaltrakts und des Pankreas eine stadiengerechte Therapie vorgeschlagen. Grundsätzlich wird für alle neuroendokrinen Tumoren eine primäre chirurgische Therapie empfohlen, auch bereits bei bestehender Metastasierung. Besondere Bedeutung hat insbesondere bei Tumoren des oberen Gastrointestinaltrakts und des Pankreas eine adäquate präoperative klinische und pathohistologische Diagnostik. Wir haben versucht die therapeutischen Richtlinien analog der Klassifikation zu vereinfachen und zu präzisieren. Es wird in vielen Fällen jedoch unabdingbar sein, eine enge Kooperation zwischen Gastroenterologen, Chirurgen und Pathologen zu pflegen, um im individuellen Fall die adäquate Therapie zu finden.
    Notes: Summary. In this review therapeutic strategies for neuroendocrine tumors of the gastrointestinal tract and the pancreas are proposed, based on the recent classification. Generally, for all neuroendocrine tumors even with obvious metastases, surgery is recommended. Particularly for neuroendocrine tumors of the upper intestinal tract and the pancreas an extensive preoperative clinical and histopathological diagnosis is required. We tried to simplify the therapeutic strategies according to the classification; in several cases, however, very close cooperation between gastroenterologists, surgeons and pathologists is necessary to decide on the appropriate therapeutic strategy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001040050159
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    326. Endobrachyoesophagus und Adenocarciom (1983)
    Springer
    Langenbeck's archives of surgery 361 (1983), S. 892-892 
    Details
    ISSN: 1435-2451
    Keywords: Columnar cell-lined lower esophagus ; Subtotal esophagectomy ; Esophageal replacement ; Endobrachyoesophagus ; Subtotale Oesophagektomie ; Speiseröhrenersatz
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Der Endobrachyoesophagus (Auskleidung des distalen Oesophagus mit Zylinderepithel statt mit Plattenepithel) stellt eine fakultative Präcancerose dar. Entsteht im distalen Oesophagus ein Adenocarcinom, so muß es wie ein Oesophaguscarcinom behandelt werden. Der Film zeigt die chirurgische Technik der subtotalen Oesophagektomie mit einzeitigem Ersatz der Speiseröhre durch Magen. Dabei wird eine spezielle intrathorakale Anastomose vorgestellt, die ein Höchstmaß an Sicherheit bietet.
    Notes: Summary The columnar cell-lined lower esophagus represents potential precancerosis. If an adeno carcinoma develops in the distal esophagus, it has to be treated as a carcinoma of the esophagus. The film shows the surgical technique of subtotal esophagectomy with simultaneous replacement of the esophagus by means of the stomach. Here a special intrathoracic anastomosis is demonstrated, which provides a high safety rate.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01276152
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    40. Der Endobrachyoesophagus als Präcancerose (1986)
    Springer
    Langenbeck's archives of surgery 369 (1986), S. 217-223 
    Details
    ISSN: 1435-2451
    Keywords: Barrett's esophagus ; Precancerous stage ; Risk factors ; Indication ; Endobrachyoesophagus ; Precanceroue ; Risikofaktoren ; Indikation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Der Endobrachyoesophagus ist eine Präcancerose, da in etwa 15 der Fälle eine maligne Entartung auftritt. Nach prospektiven Studien liegt das Risiko einer Carcinomentwicklung 30- bis 42mal höher als bei der Normalbevölkerung. Risikofaktoren für die maligne Degeneration sind Alkohol- und Nicotinabusus, chronischer gastro-oesophagealer Reflux, Zugehörigkeit zur weißen Rasse und zum männlichen Geschlecht. Eine Indikation zur Antirefluxchirurgie besteht nur beim Endobrachyoesophagus mit florider Reflux-oesophagitis. Der blande Endobrachyoesophagus bedarf einer endoskopischen Kontrolle. Das Adenocarcinom des Endobrachyoesophagus ist als Speiseröhrencarcinom anzusehen und kann wegen der vorwiegend aboralen Metastasierung durch transmediastinale Oesophagektomie behandelt werden.
    Notes: Summary Barrett's esophagus is a precancerous stage as a malign degeneration occurs in about 15 %. According to prospective studies the risk of development of cancer is 30 to 42 times higher than in the normal population. Risk factors for malign degeneration, which mostly concerns white males, are abuse of alcohol or nicotine and chronic gastroesophageal reflux. Antireflux surgery is only indicated in Barrett's esophagus in combination with active reflux esophagitis. The uncomplicated Barrett's esophagus should be controlled by endoscopy. The adenocarcinoma in Barrett's esophagus has to be considered as an esophageal carcinoma. Due to its metastatic spread in mostly aboräl direction it can be treated by blunt dissection of the esophagus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01274357
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    Paper (German National Licenses)
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