ISSN:
1432-1106
Keywords:
Epilepsy
;
GABA
;
Hippocampus
;
Inhibition
;
Kindling
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary In vitro hippocampal slices were prepared from control and commissural-kindled rats and the inhibitory processes of the dentate granule cells were assessed using paired perforant path stimulation. An early (20 ms) Cl--dependent and a late (200 ms-8 s) Cl--independent inhibition were shown to be present in the dentate. Enhancement of the late Cl--insensitive inhibition was observed following the establishment of commissural kindling and persisted for periods of up to eight weeks following the last seizure.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00237830
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