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  • Articles: DFG German National Licenses  (2)
  • Expert database systems  (1)
  • Protein S  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Computational economics 4 (1991), S. 151-163 
    ISSN: 1572-9974
    Keywords: Expert database systems ; mathematical logic and logic programming ; decision support ; travel ; knowledge representation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Economics
    Notes: Abstract L-CATA (Logic-based Computer Aided Travel Assistant) is a logic-based expert database system, which asks the user to input his query specification, such as starting place, destination, constraints, rules and goals, etc., and outputs a list of flights meeting the traveller's specification; together with an alternative list which may not quite meet the user's specification but optimizes his goals. L-CATA is written as a deductive database system, and uses heuristic rules to prune its search of the database. Unlike other air-travel related expert systems, L-CATA does not attempt to model the traveller. Instead, L-CATA complements existing Computer Reservation Systems by providing comprehensive individually tailored advice and information to the traveller. There are several approaches to implement such a system. The logic approach is a very promising one, and the aims of L-CATA can be more easily achieved by using it. In this paper, we present a logic approach to the L-CATA expert database system, and provide a theoretical foundation for such a database system.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Perspectives in drug discovery and design 1 (1994), S. 503-520 
    ISSN: 1573-9023
    Keywords: Antithrombotic proteins ; Protein C ; Protein S ; Thrombomodulin ; Recombinant proteins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary Over the last 10 years, much has been learned about the human protein C anticoagulation system, a key pathway in maintaining blood in a fluid state in vivo. Three major glycoproteins, namely protein C, protein S and thrombomodulin, are involved in this pathway. The aim of this article is to discuss therapeutic potentials and issues and challenges for developing recombinant protein C, protein S and soluble thrombomodulin as novel antithrombotics. We also briefly discuss other drug design strategies that may be employed in modulating the activity of the protein C anticoagulant pathway under pathological conditions.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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