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  • Articles: DFG German National Licenses  (1)
  • Fentanyl  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Ethanol and tetrahydroisoquinoline alkaloids do not produce narcotic discriminative stimulus effects (1983)
    Springer
    Psychopharmacology 81 (1983), S. 224-227 
    Details
    ISSN: 1432-2072
    Keywords: Discriminative stimulus ; Fentanyl ; Morphine ; Ethanol ; Tetrahydropapaveroline ; Salsolinol ; 3-Carboxysalsolinol ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Male Sprague-Dawley rats were trained in a two lever food-reinforced procedure to discriminate between the effects of saline and the synthetic narcotic analgestic fentanyl (0.04 mg/kg). After acquisition of this discrimination, generalization tests with morphine, ethanol and some tetrahydroisoquinoline alkaloids were conducted. The rats dose-dependently generalized the effect of morphine but did not generalize the effects of either ethanol, tetrahydropapaveroline, salsolinol or 3-carboxysalsolinol to the fentanyl discriminative stimulus. Thus, these data do not support a biochemical link between ethanol and opiates.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00427266
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