ISSN:
1573-5001
Keywords:
Pulsed field gradients
;
Enhanced-sensitivity NMR
;
Four-dimensional NOESY
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
Notes:
Summary An enhanced-sensitivity gradient 4D 15N, 13C-edited NOESY experiment is presented. Gradients are employed to suppress artifacts, eliminate the intense H2O signal and select for the coherence transfer pathway involving 15N magnetization. The latter use of the gradients results in a decrease in the number of phase cycle steps by a factor of two relative to the previously published 4D sequence (Kay et al., 1990) allowing for the recording of spectra with increased resolution per unit measuring time. Theoretical sensitivity enhancements of as much as a factor of $$\sqrt 2 $$ can be expected over the previously published sequence, neglecting the effects of relaxation and pulse imperfections.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00176011
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