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  • Articles: DFG German National Licenses  (3)
  • Otosclerosis  (2)
  • Gastrojejunal interposition  (1)
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  • Articles: DFG German National Licenses  (3)
Material
Years
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 238 (1983), S. 123-125 
    ISSN: 1434-4726
    Keywords: Otosclerosis ; Stapes footplate ; Cathepsin B
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cathepsin-B activity was determined fluorimetrically in the otosclerotic stapes footplate, the stapes superstructure, normal temporal cortical bone, and os frontale osteoma. Measurements with a synthetic substrate made determinations in individual samples possible. The cathepsin-B activity in the otosclerotic stapes footplate was one order of magnitude higher than that of the superstructure, which was not affected by the disease. The cortical bone and the superstructure displayed similar activities, as did os frontale osteoma and otosclerosis. The high lysosomal proteinase activity appears to be closely connected to the otosclerotic bone resorption process.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 243 (1986), S. 229-232 
    ISSN: 1434-4726
    Keywords: Myosin kinase ; Otosclerosis ; Perilymph ; Organ of Corti
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The guinea pig organ of Corti contains myosin light-chain kinase (MLCK) activity. The upper and lowermost parts of the cochlea do not show significantly different activities of the enzyme, which is Ca2+ and calmodulin-dependent. Short-term noise exposure does not cause a significant change. 0.3–5 Kilodalton substances of the otosclerotic perilymph, separated by SG-25 column chromatography, inhibit the MLCK activity in in vitro organ of Corti preparations. This inhibitory action of the perilymph substances can also be observed with the purified MLCK of turkey gizzard. The activity of the enzyme can be specifically inhibited by cyclic AMP-dependent protein kinase.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Pediatric surgery international 15 (1999), S. 132-134 
    ISSN: 1437-9813
    Keywords: Key words Esophageal stricture ; Alkaline reflux ; Esophageal replacement ; Gastrojejunal interposition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The main considerations in replacing the esophagus are to avoid postoperative necrosis of all or part of the graft, leakage or stenosis of the anastomoses, and complications related to acid-peptic or alkaline reflux. A 5-year-old boy, after two unsuccessful thoracic operations for atresia and then stenosis of the esophagus, underwent resection of the esophagus because of duodeno-gastroesophageal reflux. The continuity of the alimentary tract was restored by gastrojejunal interposition. We recommend this method of reconstruction when the esophago-gastrostoma is created in the chest, and the possibility of alkaline reflux must be considered.
    Type of Medium: Electronic Resource
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