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  • Articles: DFG German National Licenses  (2)
  • Key words NIDDM, glycogen synthase, DNA polymorphism, genetics, hypertension.  (1)
  • Key words Sjögren syndrome  (1)
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  • Articles: DFG German National Licenses  (2)
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  • 1
    Electronic Resource
    Electronic Resource
    Simple tandem repeat DNA polymorphism in the human glycogen synthase gene is associated with NIDDM in Japanese subjects (1994)
    Springer
    Diabetologia 37 (1994), S. 536-539 
    Details
    ISSN: 1432-0428
    Keywords: Key words NIDDM, glycogen synthase, DNA polymorphism, genetics, hypertension.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We investigated the possible association between alleles of a simple tandem repeat DNA polymorphism in the human glycogen synthase gene and non-obese non-insulin-dependent diabetes (NIDDM) in Japanese subjects. Nine alleles (−4G, −3G, −2G, −1G, 0G, 1G, 2G, 3G, and 4G) were identified in the study group of 164 patients with NIDDM and 115 non-diabetic subjects. The overall frequency distribution of the glycogen synthase gene alleles was significantly different between the two groups (p =0.0316). The 2G allele was found more frequently in patients with NIDDM than in non-diabetic subjects (17.7 % vs 8.7 %, p =0.0016). These results suggest that the 2G allele could be a genetic marker of NIDDM in Japanese subjects. [Diabetologia (1994) 37: 536–539]
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001250050144
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Complications of childhood Sjögren syndrome (1996)
    Springer
    European journal of pediatrics 155 (1996), S. 890-894 
    Details
    ISSN: 1432-1076
    Keywords: Key words Sjögren syndrome ; Renal tubular acidosis ; Interstitial ; nephritis ; Central nervous system ; disorder ; Chronic thyroiditis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Sjögren syndrome (SS) is a common disorder in adults and involves both glandular and extraglandular systems. We report here four cases of childhood SS complicated by chronic thyroiditis, interstitial nephritis or sweat gland inflammation. Additionally, in one of these cases, the central nervous system was involved. All of these complications are common in adult cases. Conclusion Childhood SS is a systemic “ductilitis” or “exocrinopathy” with complications which are commonly observed in adult cases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004310050509
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    Paper (German National Licenses)
    Fulltext
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