ISSN:
1434-4726
Keywords:
Key words Squamous cell carcinoma
;
Nucleolar
;
organizer region
;
Radiotherapy
;
Chemotherapy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract After irradiation or chemotherapy of tumors of the head and neck, histological alterations might be difficult to assess. In 30 cases of squamous cell carcinomas of the pharynx, changes in argyrophilic nucleolar organizer region (AgNOR) counts were investigated after therapy. After treatment a significant decrease of AgNOR counts was detected (P 〈 0.001). No significant differences could be found between groups treated with radiotherapy, chemotherapy or a combination of radiotherapy and chemotherapy. These findings suggest that AgNOR counts might be useful to assess cytotoxic effects on a subcellular level.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s004050050022
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