ISSN:
1432-1912
Keywords:
Eledoisin
;
Lacrimal Glands
;
Sjögren Syndrome
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Eledoisin was administered as eye drops (20 μg per eye) to ten healthy and ten pathological subjects suffering from hypofunction of lacrimal glands. The peptide was virtually ineffective in normal individuals but showed a striking stimulant effect in the pathological ones. Increase was very remarkable in the first minutes following administration of eledoisin, then declined but was still present after several hours. Chronic administration of eledoisin (3 times daily for 2 months) caused a moderate increase in basal secretion in 3 patients. An improvement was noted but only from a subjective point of view.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00503978
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