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  • Articles: DFG German National Licenses  (2)
  • Locomotor activity  (1)
  • poly-[butylmethacrylate]  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Behavioural effects of the nicotinic agonists N-(3-pyridylmethyl)pyrrolidine and isoarecolone in rats (1990)
    Springer
    Psychopharmacology 102 (1990), S. 521-528 
    Details
    ISSN: 1432-2072
    Keywords: Nicotine ; N-(3-pyridylmethyl)pyrrolidine ; Isoarecolone ; Nicotinic receptors ; Locomotor activity ; Drug discrimination
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The nicotinic agonists N-(3-pyridylmethyl)pyrrolidine (PMP) and isoarecolone have been compared with (−)-nicotine in three behavioural procedures and as inhibitors of [3H]-(−)-nicotine binding. Locomotor activity was recorded as movements between beams of infra-red light (ambulation). In experimentally naive rats, nicotine, PMP and isoarecolone reduced ambulation. In rats receiving nicotine chronically and previously exposed to the activity cages, nicotine and PMP increased ambulation in a dose-related manner. However, isoarecolone did not increase ambulation at doses that were active in other procedures. In rats trained to discriminate nicotine from saline in a two-bar operant conditioning procedure with food reinforcement, there was full generalization to PMP. It was also found that PMP potently inhibited the binding of [3H]-(−)-nicotine to rat brain membranes in vitro. These results were discussed with previous data for the discriminative stimulus and ligand-binding effects of isoarecolone obtained under similar conditions. The relative potency of PMP in different behavioural procedures was similar to that of (−)-nicotine. However, isoarecolone was relatively 10 times more potent in decreasing ambulation than would have been expected from its potency in the ligand-binding and discriminative stimulus procedures. The results suggest that the pharmacodynamic action of isoarecolone differs from that of nicotine and PMP, and that it will be a useful probe in further analyses of central nicotinic mechanisms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02247135
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Preparation of core-shell polymer colloid particles by encapsulation (1997)
    Springer
    Colloid & polymer science 275 (1997), S. 274-283 
    Details
    ISSN: 1435-1536
    Keywords: Key words Heterocoagulation ; polymer colloids ; poly-[styrene] ; poly-[butylmethacrylate] ; encapsulation ; core-shell particles
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract  By means of heterocoagulation anionic poly-[styrene] particles were coated with smaller electrosterically stabilised cationic particles of poly-[butyl methacrylate]. On heating the heterocoagulated units 45 °C above the glass transition temperature of poly-[butyl methacrylate], as predicted theoretically, the latter polymer spread over the surface of the poly-[styrene] particle to give a composite particle with a core-shell structure. It was found that the extent of packing of the small particles on the larger core particle was a critical feature of the coating process.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003960050081
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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