ISSN:
0006-3525
Keywords:
enzyme structure
;
protein topology
;
iron-sulfur cluster
;
topological chirality
;
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
An examination of x-ray structures of single-cluster [4Fe-4S] proteins in the Protein Data Bank has revealed that all redox proteins and the glutamine 5-phosphoribosyl-1-pyrophosphate amidotransferase from Bacillus subtilis have a topological configuration arbitrarily designated as D, whereas the DNA repair enzyme endonuclease III from Escherichia coli has the opposite topological configuration, L. This is the first example in which both senses of topological chirality have been observed in a class of proteins. © 1997 John Wiley & Sons, Inc. Biopoly 42: 411-414, 1997
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
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