ISSN:
1432-069X
Keywords:
Allergic contact dermatitis
;
Tγ cells
;
Theophylline-sensitive T lymphocytes
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Two lymphocyte subpopulations, T cells bearing a receptor for the Fc fragment of IgG (Tγ) and theophylline-sensitive T cells, were investigated in 49 patients with allergic contact dermatitis (ACD) in the acute phase and compared with a control group. Patients with ACD had markedly reduced relative Tγ and theophylline-sensitive T lymphocyte levels, compared with normals (P〈0.0005). The patients also showed reduced absolute Tγ and theophylline-sensitive T cells with respect to the controls (P〈0.01). To determine whether decreased levels of Tγ and theophylline-sensitive T cells were related to the activity of ACD, the same T-cell subsets were determined in 10 of 49 patients after the clearing of the contact dermatitis. Both T-cell subpopulations were found within the normal range.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00409252
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