ISSN:
1432-1076
Keywords:
Growth hormone deficiency
;
Wilms tumour
;
Growth hormone replacement
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Wilms tumour was found in a Japanese boy aged 5 years 9 months with isolated growth hormone (GH) deficiency and some congenital anomalies. He had received pituitary GH replacement therapy from the age of 2 years 1 month to 4 years 7 months and after a 1 year interval he received biosynthetic GH for 2 months until the tumour became clinically apparent. This was the sixth known patient with GH deficiency to develop a malignant neoplasm during or after GH replacement therapy and the first with a solid tumour in Japan since 1975, when treatment with pituitary GH for patients with GH deficiency was introduced.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01958269
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