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Cell-culture studies on neurofibromatosis (von Recklinghausen's disease) (1985)

Mao, R. ; Krone, W. ; Nothdurft, W. ; [et al.]

Springer

Archives of dermatological research 277 (1985), S. 439-443

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ISSN: 1432-069X

Keywords: Neurofibromatosis ; X-ray sensitivity ; Chromosomal breakage

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary The X-ray sensitivity of strains of fibroblast-like cells derived from peripheral neurofibromas of ten patients with neurofibromatosis was compared with that of 12 strains of skin fibroblasts derived from healthy donors. Quantitative parameters of the dose-dependent reduction in colony-forming ability did not differ significantly between these two groups of strains. The cloning efficiencies of nonirradiated controls varied within the same range in strains derived from patients and from healthy donors.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00510059

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