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  • Articles: DFG German National Licenses  (6)
  • cataracts  (2)
  • diagnosis  (2)
  • ivermectin  (2)
  • 1
    Electronic Resource
    Electronic Resource
    The diagnosis and treatment of chlamydial conjunctivitis (1988)
    Springer
    International ophthalmology 12 (1988), S. 95-99 
    Details
    ISSN: 1573-2630
    Keywords: chlamydia ; acute conjunctivitis ; neonatal conjunctivitis ; direct fluorescent antibody cytology ; diagnosis ; treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Chlamydial conjunctivitis will usually go unrecognized and therefore untreated unless it is specifically considered. The possibility of chlamydial infection must be borne in mind in neonatal conjunctivitis, in acute conjunctivitis in sexually active adults, and in chronic follicular conjunctivitis. Chlamydial conjunctivitis is often indistinguishable from other forms of conjunctivitis on clinical grounds, and accurate diagnosis is based on laboratory tests. It seems that direct fluorescent antibody (DFA) cytology offers an attractive alternative to the more complicated and time-consuming tissue culture isolation method. Once diagnosed, chlamydial infection should be treated with the appropriate systemic antibiotics, and proper posttreatment follow-up is necessary to assess the efficacy of treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00137132
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Onchocerciasis — A potential revolution in its treatment (1987)
    Springer
    International ophthalmology 11 (1987), S. 83-85 
    Details
    ISSN: 1573-2630
    Keywords: onchocerciasis ; treatment ; ivermectin ; vector control
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Onchocerciasis is a major blinding disease affecting at least 28 million people in Africa and Latin America. Although a large-scale vector control program has been highly successful in limiting transmission of infection in West Africa, there has not been a satisfactory form of treatment available for those already infected or those living in other areas. Despite the fact that two drugs, diethylcarbamazine and suramin, are active against the filarial parasite that causes onchocerciasis, their use is severely limited by their toxicity and the reaction they induce. A newly developed drug, ivermectin, appears to offer a major revolution in the treatment of onchocerciasis. In a series of clinical trials, ivermectin has been shown to be an extremely effective microfilaricide which induces only minimal side effects. Ivermectin is given as a single oral dose which can be repeated on an annual basis. In view of its safety and efficacy and its ease of administration, it seems likely that ivermectin will be suitable for use in mass chemotherapy programs against onchocerciasis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00136735
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Onchocerciasis (1990)
    Springer
    International ophthalmology 14 (1990), S. 189-194 
    Details
    ISSN: 1573-2630
    Keywords: onchocerciasis ; blindness ; ivermectin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Onchocerciasis is a devastating blinding disease caused by the parasite Onchocerca volvulus that infects about 80 million people, causing blindness and visual impairment in 1–2 million people. In hyperendemic areas, more than half of the population will become blind from onchocerciasis before they die. Blindness is the most important effect of the disease and results, in part, from direct invasion of the eye by microfilariae. The recent development of ivermectin has revolutionized our ability to treat this disease. An annual oral dose of only 150 mg/kg completely suppresses the disease manifestations. Programs for the community-based mass distribution of ivermectin are now being conducted and promise to control this major blinding scourge.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00158317
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Trachoma (1990)
    Springer
    International ophthalmology 14 (1990), S. 201-204 
    Details
    ISSN: 1573-2630
    Keywords: Trachoma ; epidemiology ; diagnosis ; health education ; control
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Trachoma causes one-quarter of the world's blindness and, although it has disappeared from many developed areas, it remains a major problem, especially in underprivileged rural areas in developing countries. Recent advances in the understanding of the molecular biology of chlamydia offer encouragement for the eventual development for an effective trachoma vaccine. Advances in the understanding of the epidemiology of trachoma, particularly of the importance of reinfection and the intrafamily transmission of infection, have led to the identification of the key importance of simple hygiene measures such as facial cleanliness in preventing the transmission of trachoma. Community-based health education intervention programs are being developed to assess the efficacy of a public health approach to the control of trachomatous blindness.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00158319
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Prevalence and causes of vision loss in central Tanzania (1991)
    Springer
    International ophthalmology 15 (1991), S. 123-129 
    Details
    ISSN: 1573-2630
    Keywords: blindness ; cataracts ; corneal opacity ; Tanzania ; trachoma ; visual impairment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A population-based survey of the prevalence of major blinding disorders was conducted in three villages in central Tanzania. Overall, 1827 people overthe age of seven years old were examined. In those age seven and older, the prevalence of bilateral blindness (visual acuity in the better eye of 〈3/60) was 1.26% and monocular blindness (visual acuity of 〈3/60 in one eye) was 4.32% and the prevalence of visual impairment (visual acuity 〈6/18 but ≥3/60 in both eyes was 1.04% and in one eye was 1.75%. Corneal opacities were responsible for 44% of bilateral and 39% of monocular blindness and resulted from trachoma, measles often in association with Vitamin A deficiency, keratoconjunctivitis, and the use of traditional eye medicines. Cataracts accounted for 22% of bilateral and 6% of monocular blindness. Readily preventable or reversible causes of blindness were responsible for 65% of cases of bilateral and 46% of monocular blindness.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01046432
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Prevalence and causes of vision loss in central Tanzania (1991)
    Springer
    International ophthalmology 15 (1991), S. 123-129 
    Details
    ISSN: 1573-2630
    Keywords: blindness ; cataracts ; corneal opacity ; Tanzania ; trachoma ; visual impairment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A population-based survey of the prevalence of major blinding disorders was conducted in three villages in central Tanzania. Overall, 1827 people overthe age of seven years old were examined. In those age seven and older, the prevalence of bilateral blindness (visual acuity in the better eye of 〈3/60) was 1.26% and monocular blindness (visual acuity of 〈3/60 in one eye) was 4.32% and the prevalence of visual impairment (visual acuity 〈6/18 but ≥3/60 in both eyes was 1.04% and in one eye was 1.75%. Corneal opacities were responsible for 44% of bilateral and 39% of monocular blindness and resulted from trachoma, measles often in association with Vitamin A deficiency, keratoconjunctivitis, and the use of traditional eye medicines. Cataracts accounted for 22% of bilateral and 6% of monocular blindness. Readily preventable or reversible causes of blindness were responsible for 65% of cases of bilateral and 46% of monocular blindness.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00224465
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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