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The effect of cycloheximide on nuclear uH2A content (1984)

Dalay, N. ; Kirdar, B. ; Bermek, E.

Springer

Cellular and molecular life sciences 40 (1984), S. 1398-1399

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ISSN: 1420-9071

Keywords: Rat liver ; liver, rat ; chromatin, rat liver ; cycloheximide ; nonhistone protein

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary The effect of intraperitonal cycloheximide administration on acid-soluble rat liver chromatin proteins has been investigated by electrophoresis in acetic acid-urea polyacrylamide gels. A nonhistone protein, which migrates between oxidized histone H3 and histone H1 has been found tobe increased in amount following cycloheximide treatment. This protein seems to be identical with semihistone protein H24 (uH2A). A possible relationship of uH2A to the inhibition of rRNA synthesis is discussed.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01951910

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