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  • Articles: DFG German National Licenses  (2)
  • oxygenation  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of experimental biology and medicine 121 (1996), S. 465-467 
    ISSN: 1573-8221
    Keywords: perfluorodecalin ; blood ; oxygenation ; blood protection
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The ability of perfluorodecalin to improve the properties of blood and protect it from harmful agents was assessed by evaluating the functional state of donor blood treated with this compound and then exposed to O2 in a bubble (contact) oxygenator. The results of determining the acidic resistance of erythrocytes, serum levels of free hemoglobin, the amount of malonic dialdehyde in lipid extracts of erythrocyte membranes, erythrocyte deformability, and blood viscosity support the notion that organoperfluoric compounds are chemically and biologically inert. Pretreatment of blood with perfluorodecalin protects it from the adverse effects of contact oxygenation and improves its rheological properties.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of experimental biology and medicine 120 (1995), S. 1157-1161 
    ISSN: 1573-8221
    Keywords: perfluorodecalin ; blood ; oxygenation ; electron microscopy ; morphological changes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The hemoprotective effect of perfluorocarbons was studied by examining the surface architectonics of red cells during exposure of the blood to perfluorodecalin and contact oxygenation. Scanning electron microscopy revealed an, appeciable increase in the percentage of damaged erythrocytes directly exposed to oxygen in a contact oxygenator. Interaction between blood and perfluorodecalin not only does not impair the morphology of the blood, but also prevents untoward effects of subsequent contact oxygenation. Fluorocarbon treatment of the blood gives rise to a number (up to 17–18%) of special cells, which morphologically represent somewhat altered normocytes with increased resistance, this reflecting a specific reaction of the blood to perfluorodecalin.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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