ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] Many CF-associated mutations, including the most common AF508, cause a defect in protein processing and a failure of mutant CFTR to reach the apical membrane6'19"21. To assess the processing and function of R117H, R334W, and R347P, we expressed wild-type and mutant CFTRs in Fischer rat thyroid ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/362160a0
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