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  • Articles: DFG German National Licenses  (3)
Source
  • Articles: DFG German National Licenses  (3)
Material
Years
  • 1
    Electronic Resource
    Electronic Resource
    Bayesian Statistical Studies of the Ramachandran Distribution (2005)
    Berkeley, Calif. : Berkeley Electronic Press (now: De Gruyter)
    Statistical applications in genetics and molecular biology 4.2005, 1, art35 
    Details
    ISSN: 1544-6115
    Source: Berkeley Electronic Press Academic Journals
    Topics: Biology
    Notes: We describe a method for the generation of knowledge-based potentials and apply it to the observed torsional angles of known protein structures. The potential is derived using Bayesian reasoning, and is useful as a prior for further such reasoning in the presence of additional data. The potential takes the form of a probability density function, which is described by a small number of coefficients with the number of necessary coefficients determined by tests based on statistical significance and entropy. We demonstrate the methods in deriving one such potential corresponding to two dimensions, the Ramachandran plot. In contrast to traditional histogram-based methods, the function is continuous and differentiable. These properties allow us to use the function as a force term in the energy minimization of appropriately described structures. The method can easily be extended to other observable angles and higher dimensions, or to include sequence dependence and should find applications in structure determination and validation.
    Type of Medium: Electronic Resource
    URL: http://www.bepress.com/sagmb/vol4/iss1/art35
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Amino-acids in Corn-steep (1962)
    [s.l.] : Nature Publishing Group
    Nature 195 (1962), S. 503-504 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] For the quantitative determination of some amino-acids we have used the method of descending electro-phoresis according to Mikes5 and Bode's evaluation method6. The methods of cultivation of the strain of Penicillium chrysogenum NG on a rotary shaker and the analytical methods used have been ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/195503a0
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  • 3
    Electronic Resource
    Electronic Resource
    Volumetrische Bestimmung von Beryllium und freier SÄure nebeneinander (1967)
    Springer
    Fresenius' Zeitschrift für analytische Chemie 229 (1967), S. 184-188 
    Details
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Zur indirekten volumetrischen Bestimmung von Beryllium wird die nach Reaktion mit Salicylat freigesetzte SÄure alkalimetrisch titriert. Freie SÄure in Berylliumlösungen kann nach Maskierung des Be mit Fluorid ebenfalls alkalimetrisch titriert werden. Zur Nebeneinanderbestimmung von Beryllium und freier SÄure wird in einem aliquoten Teil nach Zusatz von Fluorid die freie SÄure bestimmt und in einem weiteren aliquoten Teil nach Zusatz von Salicylat die Summe von SÄure und Beryllium. Die relativen Fehler betragen maximal ±2%. Die Berylliumbestimmung wird von Al, Ti, Fe, U und anderen Ionen, die mit Salicylat starke Komplexe bilden, gestört. La und Zn können mit Oxalat maskiert werden. Mg kann bis zu einem 10fachen überschu\ vorhanden sein.
    Notes: Summary An indirect volumetric determination of beryllium is based on the liberation of acid by reaction with salicylate and its alkalimetric titration. Free acid in Be solutions can also be titrated alkalimetrically after masking of Be with fluoride. For the determination of free acid and beryllium in presence of each other an aliquot is used for the determination of free acid after addition of fluoride and another one for the determination of the sum of Be and free acid after addition of salicylate. Relative errors are ± 2% at the most. Al, Ti, Fe, U and other ions forming strong complexes with salicylate interfere with the beryllium determination. La and Zn can be masked by oxalate. Mg can be present in a 10-fold excess.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00513752
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    Paper (German National Licenses)
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