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  • Electronic Resource  (3)
  • 1980-1984  (3)
  • 1940-1944
  • 1980  (3)
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  • Electronic Resource  (3)
Years
  • 1980-1984  (3)
  • 1940-1944
Year
  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental dermatology 5 (1980), S. 0 
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A boy with an ectodermal dysplasia is presented, together with clinical and laboratory findings. Description of members of the family is included and comparison made with other ectodermal dysplasia syndromes now known to exist. This family closely resembles the recently delineated ‘tooth and nail’ syndrome.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-9686
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract Conventional peripherally invasive mechanical circulatory assist methods such as intra-aortic balloon pumping are of only limited hemodynamic benefit in cases of severe left ventricular failure. This article deals with the analysis and testing of a new pumping concept (16), that is theoretically capable of providing adequate circulatory and respiratory assistance in cases of severe uni- or biventricular failure. This assist system combines an intra-aortic balloon pump (a series form of left ventricular assistance) and pulsatile venoarterial membrane oxygenator bypass (a parallel mode of assistance). The combined pulsatile assist system is controlled by a digital microprocessor which provides appropriate phasing relative to the R wave of the ECG. This support system requires only cannulation of femoral or other easily exposed vessels. Blood-gas exchange gas diffusion or massive pulmonary embolism or other perfusion defects. This concept has been tested in a series of experiments with canine models of ventricular failure. The results of this study indicate that (1) balloon pumping becomes much more effective when combined with pulsatile veno-arterial bypass in cases of severe ventricular failure with an attendant hypotensive circulatory state, and (2) the automatic control system is effective in optimizing the performance of the combined assist system.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Annals of biomedical engineering 8 (1980), S. 209-224 
    ISSN: 1573-9686
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract An automatic control scheme for the control of intra-aortic balloon pumping has been implemented on a Digital Equipment Corporation LSI-11 micro-processor system and tested in experiments conducted on a mock circulatory loop as well as in a series of acute animal experiments. The control algorithm employed by the digital controller (LSI-11) is identical in form to that employed by Clark et al. (3), and consists of [1] the beat-by-beat evaluation of a performance index that reflects the objectives of balloon pumping, and [2] the adjustment of balloon inflation and deflation times within the diastolic period so as to maximize this performance index according to a steepest ascent algorithm. In order to reduce convergence time and minimize disturbances around the optimum operating point, a scheme that reduces search step size as the search proceeds from initial values is also incorporated in the algorithm. Importantly, this system obeys a bedside measurement constraint in that it requires only readily available physiologic signals for its operation; the ECG for timing purposes, and the central aortic pressure for evaluation of the system performance index. A number of conventional safety features are also implemented in the controller to, for example, guard against untimely balloon inflation in the occurrence of aberrant heart beats. Finally, the ability of this digital controller to reach an optimum independent of the dynamics of the particular pneumatic pumping system utilized, coupled with the flexibility in design capability and relatively low cost of implementation via the microprocessor system, provide a significant advance in the area of the automatic control of intra-aortic balloon pumping.
    Type of Medium: Electronic Resource
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