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  • Electronic Resource  (2)
  • 2000-2004
  • 1990-1994  (2)
  • 1991  (2)
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  • Electronic Resource  (2)
Years
  • 2000-2004
  • 1990-1994  (2)
Year
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 82 (1991), S. 55-59 
    ISSN: 1432-0533
    Keywords: Germanium intoxication ; Mitochondrial myopathy ; Ragged-red fiber ; Autophagic vacuole
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The long-term administration of germanium dioxide (GeO2) to rats produced Ge myopathy characterized by the formation of ragged-red fibers. The earliest pathological changes in experimental Ge myopathy were a decrease in cytochrome c oxidase activity and accumulation of high electron-dense materials in mitochondria. These findings suggest that a mitochondrial dysfunction may be most important in the genesis of experimental Ge myopathy, which could be a useful animal model for the investigation of and therapeutic trials for human mitochondrial myopathies.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 238 (1991), S. 47-48 
    ISSN: 1432-1459
    Keywords: Carbamate ; Polyneuropathy ; Axonal degeneration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A 55-year-old woman who attempted suicide by ingesting 200 ml of m-tolyl methyl carbamate (MTMC) is reported. She was comatose for 3 days and, upon recovery, had notable paraesthesia in her lower limbs and difficulty in walking. Neurological examination revealed sensorimotor polyneuropathy. Sural nerve biopsy revealed marked axonal degeneration with a moderate decrease of myelinated fibres.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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