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  • 1
    Electronic Resource
    Electronic Resource
    [s.l.] : Macmillian Magazines Ltd.
    Nature 405 (2000), S. 48-50 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Streams of dust emerging from the direction of Jupiter were discovered in 1992 during the flyby of the Ulysses spacecraft, but their precise origin within the jovian system remained unclear. Further data collected by the Galileo spacecraft, which has been orbiting Jupiter since December ...
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of nutrition 18 (1979), S. 51-61 
    ISSN: 1436-6215
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Summary The effect of coffee without and with caffeine (200 mg) on the performance of “awake” respectively “fatigued” subjects was proved. 5 females and 7 males (22 to 32 years) were chosen for the cross-over double-blind study. Motor reaction time, visual-mental processing time, reading-speed and reading-errors were recorded. Further experiments under aggravated conditions were carried out. In the morning (“awake”) caffeine increases the efficiency of all parameters excepted the reading errors. At night (“fatigued”) the increase by caffeine is insignificant. Even in some subjects caffeine decreases the speed of reading and increases the number of errors. Under test-conditions, which were aggravated by strong acoustical disturbance, caffeine does not improve efficiency, compared with caffeine-free coffee. Overriding into the range of decreasing performance in spite of increasing central activity was not found under any test-condition.
    Notes: Zusammenfassung In einer Doppelblindstudie wurden an 12 Probanden im Alter von 22 bis 32 Jahren die Wirkung von koffeinhaltigem und koffeinfreiem Kaffee für zwei Befindenszustände „wach“ und „müde“ untersucht. Bei gleicher Dosierung von 200 mg Koffein wurden die Parameter motorische Reaktions-, die visuell-mentale Verarbeitungszeit sowie die Lesegeschwindigkeit und die Lesefehler registriert. Zusätzlich wurden Messungen unter erschwerten Bedingungen durchgeführt. Im Befindenszustand „wach“ am Morgen wirkt koffeinhaltiger Kaffee bis auf die Lesefehler in allen Parametern signifikant leistungssteigernd. Nachts, im Befindenszustand „müde“, bewirkt koffeinhaltiger Kaffee nur eine unwesentliche Leistungsverbesserung. Bei den Parametern Lesegeschwindigkeit und Lesefehler ist mit Koffein bei einzelnen Versuchspersonen eine Leistungseinbuße feststellbar. Auch unter Versuchsbedingungen mit erhöhten Anforderungen durch akustischen Störeinfluß war unter Koffein keine Leistungserhöhung gegenüber koffeinfreiem Kaffee zu beobachten. Eine übersteuerung in den Bereich abnehmender Leistung bei zunehmender Aktivität fand unter keiner Versuchsbedingung statt.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 273 (1975), S. 325-330 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract 199Hg Fourier Transform NMR studies of various solutions of diverse mercury salts in H2O and D2O or in the appropriate protonated and deuterated acids are reported for both Hg 2 ++ and Hg++. In the different solutions investigated the199Hg line positions depend on the concentration of the solution, on the solvents and their isotopic composition and on the temperature of the sample. A ratio of the Larmor frequency of199Hg and of2H in a Hg(NO3)2 solution in dilute DNO3 is given. Using this ratio and the measured chemical shifts, a ratio of the Larmor frequencies of199Hg for infinite dilution relative to2H in pure D2O is given. From this a gI-factor for199Hg is derived and compared with the gI-factor of an optical pumping experiment. The resulting shielding constant is σ* (hydrated199Hg++ versus199Hg atom)=−24.32(5) · 10−4. This yields an atomic reference scale for all measured NMR line shifts of mercury.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 287 (1978), S. 7-13 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The connection between resonances occuring in the scattering of electrons on atoms (molecules) with or without the presence of a classical laser field is demonstrated for aN-state model-atom in 1st order perturbation theory with respect to the laser field. It is possible to predict the position, the shape and the background of resonances in the laser field from the sole knowledge of the corresponding scattering amplitudes without the laser field. At first, a soft-photon approximation for individual partial wave amplitudes is derived. This approximations is then tested numerically for a 2-state square well potential model. Details about the accuracy of the soft-photon approximation are obtained by comparing with the numerically exact results. Finally our findings are applied to give an interpretation of recent experimental data.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 79 (1992), S. 479-480 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of environmental contamination and toxicology 44 (1990), S. 8-12 
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1433-0407
    Keywords: Schlüsselwörter Pramipexol ; Ropinirol ; Narkolepsie ; Tagesmüdigkeit ; Keywords Pramipexole ; Ropinirole ; Narcolepsy ; Daytime sleepiness
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract Recently, sudden “sleep attacks” have been described in parkinsonian patients taking the nonergoline dopamine agonists pramipexole and ropinirole. Due to this possible side effect, patients must be instructed not to drive vehicles and to refrain from other activities carrying the risk of self-injury. However, the very existence of sleep attacks remains controversial in sleep medicine, since a gradual transition from wakefulness to sleep is normally observed. Accordingly, sudden onset of sleep, e.g., in narcolepsy or sleep apnea syndrome, is usually associated with excessive daytime sleepiness. Prevalence of sleep disorders and daytime sleepiness have been shown to be increased in Parkinson's disease. Nonergoline dopamine agonists are already known to induce somnolence. Currently, it is not predictable whether sleep attacks represent a sudden transition from wakefulness to sleep or result from an increased propensity to fall asleep, with patients perceiving a sudden onset. Possible pathophysiological mechanisms and legal implications of sleep attacks are discussed.
    Notes: Zusammenfassung Im Zusammenhang mit der Einnahme der Nonergolin-Dopaminagonisten Pramipexol und Ropinirol wurde vor kurzem das Auftreten plötzlicher “Schlafattacken” bei Parkinson-Patienten postuliert. Aufgrund dieser möglichen Nebenwirkung müssen mit Pramipexol oder Ropinirol behandelte Patienten darauf hingewiesen werden, kein Kraftfahrzeug zu führen und keine anderen Aktivitäten, bei denen ein Mangel an Aufmerksamkeit zu Selbst- oder Fremdgefährdung führt, auszuüben. Aus schlafmedizinischer Sicht gilt das Auftreten von “Schlafattacken” jedoch als ungewöhnlich, da ein allmählicher Übergang aus dem Wach- in den Schlafzustand angenommen wird. So ist das z. B. bei der Narkolepsie oder dem Schlafapnoesyndrom beschriebene rasche Einschlafen in der Regel mit vorbestehender Tagesmüdigkeit assoziiert. Schlafstörungen und Tagesmüdigkeit weisen eine hohe Prävalenz bei der Parkinson-Krankheit auf. Zudem ist Schläfrigkeit als Nebenwirkung der Nonergolin-Dopaminagonisten bereits bekannt. Zum jetzigen Zeitpunkt ist nicht vorhersagbar, ob es sich bei den “Schlafattacken” um einen plötzlichen Übergang aus dem Wach- in den Schlafzustand handelt oder diese überwiegend als Folge eines subjektiv als plötzlich empfundenen Einschlafens bei vorbestehender Tagesmüdigkeit zu interpretieren sind. Mögliche pathophysiologische Mechanismen des Phänomens der “Schlafattacken” sowie rechtliche Implikationen aus der Aufklärungspflicht des Arztes werden in diesem Beitrag diskutiert.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Archives of environmental contamination and toxicology 3 (1975), S. 352-363 
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract The distribution and decay rates of dislodgeable residues of azinphosmethyl applied by two types of air blast sprayers on apple foliage in Ohio were investigated. Leaf discs were taken from nine sites located on the periphery of Cortland apple trees at five dates after spraying. The sprayer delivering the higher airflow rate, but lower velocity, deposited the pesticide much more uniformly over the trees and applied more in the top of the tree. The other sprayer deposited the greatest proportion of pesticide on the site nearest the sprayer. The residue decreased at all sites and ranged from 42 to near 100% decrease at 14 days after spraying.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 73 (2000), S. 401-409 
    ISSN: 1432-1246
    Keywords: Key words Methylformate ; Neurobehavioral effects ; Experimental exposure ; Wiener test system
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objectives: The aim of the study was to investigate the acute effects of experimental methylformate exposure on the nervous system. Methods: In an exposure chamber, 20 subjects were exposed to methylformate at 100 ppm [Swiss maximum allowable concentration (MAC)] for 8 h. The same number of subjects with the same ages (between 20 and 30 years), gender and education level (university) were examined by the same procedure as a control group. The subjects did not know if they were exposed or not. Three times (morning, noon, evening) during these 8 h, mood [Profile of Mood States (POMS)], neurobehavioral performance (reaction, Stroop, nonverbal learning, determination, tracking; Wiener Test System), vision (visual acuity, contrast sensitivity, color sensitivity) and postural sway were tested. During an undemanding test (POMS) and a demanding performance task (determination test), pulse, electromyography (EMG) of the forehead and of the neck were recorded. In the morning and evening spirometry [forced vital capacity (FVC), forced one-second expiration volume (FEV), medium expiration flow (MEF) and peak expiration flow (PEF)] and the odor perception threshold were measured. Results: In the evening, in the exposed group, fatigue was significantly increased and the EMG of the forehead during a demanding task showed a different development during exposure. The other tests showed no significant solvent effect, but 16 of 43 test parameters showed a significant effect of time. Conclusions: The results of this study indicate a possible effect of methylformate exposure on the subjective feeling of fatigue after 8 h exposure at 100 ppm in young and healthy subjects, without measurable impairment of neurobehavioral performance. We assume that a similar effect in normal work, combined with a heavy workload and shift work, can lead to an impairment of productivity, and increase the risk of accidents.
    Type of Medium: Electronic Resource
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