Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Electronic Resource  (3)
  • 2000-2004
  • 1985-1989  (3)
  • 1950-1954
  • 79.20.D  (1)
  • Ampullary/pancreatic cancer  (1)
  • Anxiety  (1)
Material
  • Electronic Resource  (3)
Years
  • 2000-2004
  • 1985-1989  (3)
  • 1950-1954
Year
Keywords
  • 1
    ISSN: 1432-0649
    Keywords: 42.60.K ; 79.20.D ; 81.60 ; 82.50
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The photoablation of polystyrene (PS) and polymethylmethacrylate (PMMA) was studied in real-time during the uv laser pulse at 193 nm. The transmission and total reflection of thin polymer layers on quartz glass substrates was measured time-resolved. From the results for the strongly absorbing PS it can be concluded that the emission of material starts within the first few nanoseconds of the laser pulse. Photoablation of PMMA, which is a relatively weak absorber at 193 nm, is accompanied by strong modifications of the transmission by the first several ten laser pulses.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    ISSN: 1432-2072
    Keywords: Benzodiazepines ; Triazolopyridazines ; Corticosterone ; Anxiety ; Stress
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Fifteen minute exposure to a novel environment plus 120 dB sound stimulation produced a three-fold increase in serum corticosterone concentrations in rats. A low dose of intraperitoneally (IP) administered chlordiazepoxide (CDP) (5 mg/kg) attenuated this response, whereas a higher dose (20 mg/kg) elevated corticosterone concentrations in rats not subjected to sound stress. Parallel results were obtained after intracerebroventricular (ICV) drug administration, with a low dose of CDP (5 μg) reducing the sound stress response and higher doses (25 and 50 μg) increasing corticosterone concentrations in unstressed animals. Thus, despite the presence of benzodiazepine (BDZ) receptors at every level of the hypothalamic-pituitary-adrenocortical axis, it appears that BDZs alter the activity of this system via an interaction with BDZ receptors in brain. CL 218,872 (2.5–20 mg/kg), a novel non-BDZ anxiolytic compound, did not attenuate the corticosterone elevation produced by sound stimulation, and also failed to alter baseline corticosterone concentrations in unstressed animals. The fact that CL 218,872 is a selective agonist for brain Type I BDZ receptors suggests that BDZs are not influencing corticosterone secretion through an interaction with this BDZ receptor subtype. Furthermore, these results indicate that stress (as measured by pituitary-adrenocortical activation) can be dissociated from anxiety (as measured by conflict paradigms), thus challenging the validity of the corticosteroid stress test as a screening procedure for anxiolytic activity.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 365 (1985), S. 169-178 
    ISSN: 1435-2451
    Keywords: Ampullary/pancreatic cancer ; Staging ; TNM ; Therapy ; Prognosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Von 1974 bis 1982 wurden an der Chirurgischen Universitätsklinik Münster 607 Patienten mit Erkrankungen des Pankreas behandelt, von denen 256 an einem Pankreas- und 42 an einem Papillencarcinom erkrankt waren. Alle wurden nach einem dort eigens entwickelten TNM-System für das Pankreascarcinom eingeteilt. Es ergab sich bei den durchgeführten kurativen Resektionen (n = 73), die für die das Papillencarcinom einen Anteil von 78,6% und für das Pankreascarcinom von 15,6% an den Gesamtoperationen hatten, ein deutliches Überwiegen der frühen Stadien für ersteres (T1N0M0/T2N0M0 〉 60%), der späteren Stadien für letzteres (T1N0M0/T2N0M0 = 25%). Die Fernmetastasenhäufigkeit bezogen auf alle Patienten unterschied sich mit 9,5% bzw. 43,4% ebenfalls signifikant (p 〈 0,05). Bei einem niedrigen Median der Überlebenszeiten für die palliativen Eingriffe ergab sich für die Whipple-OP ein Median von 40,3 Monaten, für die totale Pankreatektomie von 28,0 Monaten. Für das Stadium T1N0M0/T2N0M0 war der Median 〉 63 Monate.
    Notes: Summary From 1974 to 1982 607 patients with diseases of the pancreas were treated at the Surgical University Clinic of Münster/West Germany. 256 of those suffered from pancreatic and 42 from ampullary cancer. All patients were grouped according to a TNM-System for pancreatic cancer developed for that particular purpose. Of the curative resections performed (n = 73) with a resection rate of 78.6% for ampullary and 15.6% for pancreatic cancer, a distinct preponderance of early stages (T1N0M0/T2N0M0 〉 60%) was noticed for the first, of late stages for the latter (T1N0M0/T2N0M0 = 25%). The frequencies of distant metastases for all operations also differed significantly, being 9.5% respectively 43.4% at the time of operation (p 〈 0.05). At the low mean survival time for palliative operations an mean survival time of 40.3 months for the Whipple operation was evaluated, of 28.0 months for total pancreatectomy. At the stage T1N0M0/T2N0M0 the mean survival time was 〉 63 months.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...