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  • 1
    Electronic Resource
    Electronic Resource
    Radiochemical synthesis and photochemical properties of the uncoupler 2-azido-4-nitrophenol, a versatile photoaffinity labeling reagent (1979)
    s.l. : American Chemical Society
    Biochemistry 18 (1979), S. 1019-1025 
    Details
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/bi00573a014
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  • 2
    Electronic Resource
    Electronic Resource
    Comparison of sample preparation techniques for gas chromatographic analysis (1977)
    s.l. : American Chemical Society
    Journal of agricultural and food chemistry 25 (1977), S. 440-445 
    Details
    ISSN: 1520-5118
    Source: ACS Legacy Archives
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jf60211a027
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  • 3
    Electronic Resource
    Electronic Resource
    High-gain coupled InGaAs quantum well InAs quantum dot AlGaAs–GaAs–InGaAs–InAs heterostructure diode laser operation (2002)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 80 (2002), S. 1126-1128 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Data are presented showing that a single-layer InAs quantum dot (QD) laser in the AlGaAs–GaAs–InGaAs–InAs heterostructure system is improved in gain and continuous wave (cw) room temperature operation by coupling, via tunneling, auxiliary strained-layer InGaAs quantum wells (QWs) to the single InAs QD layer to assist carrier collection and thermalization. A QW-assisted single-layer InAs QD laser, a QD+QW laser, is demonstrated that operates cw (300 K), and at diode length 150 μm in pulsed operation exhibits gain as high as ∼100 cm−1. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1451989
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  • 4
    Electronic Resource
    Electronic Resource
    Coupled strained-layer InGaAs quantum-well improvement of an InAs quantum dot AlGaAs–GaAs–InGaAs–InAs heterostructure laser (2001)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 79 (2001), S. 4500-4502 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Data are presented showing that, besides the improvement in carrier collection, it is advantageous to locate strain-matching auxiliary InGaAs layers [quantum wells (QWs)] within tunneling distance of a single-quantum-dot (QD) layer of an AlGaAs–GaAs–InGaAs–InAs QD heterostructure laser to realize also smaller size QDs of greater density and uniformity. The QD density is changed from 2×1010/cm2 for a 50 Å GaAs coupling barrier (QW to QD) to 3×1010/cm2 for a 5 Å barrier. The improved QD density and uniformity, as well as improved carrier collection, make possible room-temperature continuous-wave (cw) QD+QW laser operation (a single InAs QD layer) at reasonable diode length (∼1 mm), current density 586 A/cm2, and wavelength 1057 nm. The cw 300 K coupled InAs QD and InGaAs QW AlGaAs–GaAs–InGaA–InAs heterostructure lasers are grown by metalorganic chemical vapor deposition. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1430025
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  • 5
    Electronic Resource
    Electronic Resource
    Room-temperature continuous photopumped laser operation of coupled InP quantum dot and InGaP quantum well InP–InGaP–In(AlGa)P–InAlP heterostructures (2001)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 79 (2001), S. 1956-1958 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Data are presented demonstrating continuous 300 K photopumped InP quantum dot (QD) laser operation (656–679 nm) realized by modifying and coupling, via tunneling, an auxiliary InGaP quantum well (QW) to the QDs of an InP–In(AlGa)P–InAlP heterostructure grown by metalorganic chemical vapor deposition. The In0.49Ga0.51P QW coupled to the InP QDs by a thin ((approximately-less-than)20 Å) In0.5Al0.3Ga0.2P barrier overcomes the limitations of carrier collection, lateral transport, and thermalization in the QDs, thus yielding a different form of QD laser. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1405153
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  • 6
    Electronic Resource
    Electronic Resource
    Coupled InP quantum-dot InGaP quantum well InP–InGaP–In(AlGa)P–InAlP heterostructure diode laser operation (2001)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 79 (2001), S. 3215-3217 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Data are presented showing that a p–n InP–In0.5Ga0.5P–In0.5(Al0.3Ga0.2)P–In0.5Al0.5P quantum-dot (QD) heterostructure diode, with an auxiliary ∼20 Å InGaP quantum well (QW) coupled via an In(AlGa)P barrier (∼20 Å) to the single layer of QDs to aid carrier collection, has a steeper current–voltage characteristic than the case of a similar diode with no auxiliary QW. The p–n InP+InGaP QD+QW diode is capable of 300 K visible-spectrum QD laser operation, while the single-layer InP QD diode (single QD layer) saturates at low current ((approximately-less-than)1 mA) and does not exhibit stimulated emission. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1416158
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  • 7
    Electronic Resource
    Electronic Resource
    Coupled-stripe quantum-well-assisted AlGaAs–GaAs–InGaAs–InAs quantum-dot laser (2002)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 80 (2002), S. 3045-3047 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Data are presented on the coupled-stripe laser operation (continuous wave, 300 K) of a single InAs quantum-dot (QD) layer coupled via a thin (5 Å) GaAs barrier to an auxiliary strained InGaAs quantum well (QW) grown (confined) in an AlGaAs–GaAs heterostructure. Because of strain-induced (QW strain) improvement of the QD growth and QD alignment along diagonal (reflecting) ridges, the InGaAs-QW+InAs-QD crystals exhibit high gain along and across laser stripes, which is advantageous for coupled-stripe laser operation. A twin-stripe single-QD-layer QW+QD laser (4 μm stripes on 6 μm centers) of usual cleaved length, 〈 500 μm, is capable of continuous 300 K operation, with only probe heat-sink clamping and testing, at 〉50 mW. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1473686
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  • 8
    Electronic Resource
    Electronic Resource
    An ALS mouse model with a permeable blood–brain barrier benefits from systemic cyclosporine A treatment (2004)
    Oxford, UK : Blackwell Science Ltd
    Journal of neurochemistry 88 (2004), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: To test potentially beneficial drugs to amyotrophic lateral sclerosis (ALS), we created an ALS mouse model with a permeable blood–brain barrier, by crossing the G93A-SOD1 transgenic mouse with a multiple drug resistance type 1a/b (mdr1a/b) gene knockout mouse. To validate the model, we administered cyclosporine A intraperitoneally to the mice. Cyclosporine A accumulated in the brain and spinal cord of this mouse model, whereas it was unable to penetrate the CNS of mdr1a/b wild-type animals. Systemic administration of cyclosporine A extended the life of the double-mutant male mice by approximately 12%. Surprisingly, the effect was more robust in male mice and only marginal in female mice. These results demonstrate the usefulness of this combined mouse model for the testing of potentially therapeutic drugs and support the role of mitochondrial-mediated apoptosis in the pathway to motor neuron death in SOD1-associated ALS.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1471-4159.2003.02181.x
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  • 9
    Electronic Resource
    Electronic Resource
    Kinetics of in vitro bovine keratohyalin synthesis (1976)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 95 (1976), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A system is described for the study of the in vitro synthesis of bovine keratohyalin for periods of up to 24 h. Keratohyalin granules appeared morphologically unaltered during culture, although histo-chetnical stains for RNA indicate a markedly diminished RNA content by 6 h. Incorporation of tritiated histidine began slowly, then became linear between 4 and 24 h in serum-containing media. However, following pre-incubation in serum-free media, increased incorporation occurred from time zero. The internal variation of the system using a standard 6 h pulse was ±10, ±24, ±22, ±18%, in four separate experiments. Measurements of modulations in bovine keratohyalin synthesis in vitro may prove useful in the development of drugs of therapeutic potential in dermatology.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1976.tb00813.x
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  • 10
    Electronic Resource
    Electronic Resource
    METHODS AND DATA REQUIREMENTS FOR RIVER-QUALITY ASSESSMENT (1975)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the American Water Resources Association 11 (1975), S. 0 
    Details
    ISSN: 1752-1688
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Architecture, Civil Engineering, Surveying , Geography
    Notes: : The U.S. Geological Survey is now (1975) conducting an intensive river-quality assessment of the Willamette River basin, Oregon. The objectives are to (1) define a practical framework for conducting comprehensive river-quality assessments, (2) develop and document methods for evaluating basin-development alternatives in terms of potential impacts on river quality, (3) determine the kinds and amounts of data required to adequately assess various types of river-quality problems, and (4) apply the framework, data, and methods to assess the existing or potential river-quality problems of the Willamette River basin. This paper covers objectives 2, 3, and 4 by examining the rationales behind the selection and application of methods and the design of data programs for assessing specific river-quality problems. The rationales are those developed for assessing (1) the effect of population and industrial growth and resulting waste discharges on river-dissolved oxygen, (2) the potentially harmful effects on land and river quality of accelerated erosion resulting from intensive land-use development, and (3) the potential for nuisance algal growth. The goal of the assessment program and, thus, the context of the rationales is to provide technically sound information that is appropriate and adequate for resource planning and management.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1752-1688.1975.tb01822.x
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