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  • Electronic Resource  (33)
  • 1995-1999  (17)
  • 1985-1989  (16)
  • 1960-1964
  • 1
    Electronic Resource
    Electronic Resource
    A low temperature scanning tunneling microscope for use in high magnetic fields (1995)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 66 (1995), S. 4146-4149 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: We describe the design and performance of a low temperature (1.3–4.2 K) scanning tunneling microscope (STM) setup that can be used in magnetic fields up to 9.5 T. Due to the compact, rigid, and concentric design, the STM is very insensitive to external vibrations. The influence of external magnetic fields on the performance of the STM has been minimized by making a version completely out of titanium (instead of stainless steel). The STM routinely shows atomic resolution on various samples over the whole magnetic field range. We demonstrate the spectroscopic capability by local spectroscopy of the Abrikosov flux lattice on NbSe2. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1146492
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  • 2
    Electronic Resource
    Electronic Resource
    Structural selectivity of topological indexes in alkane series (1985)
    s.l. : American Chemical Society
    Journal of chemical information and modeling 25 (1985), S. 23-27 
    Details
    ISSN: 1520-5142
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ci00045a006
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Cooperativity of tetrodotoxin action in the frog node of Ranvier (1985)
    Springer
    Pflügers Archiv 405 (1985), S. 237-243 
    Details
    ISSN: 1432-2013
    Keywords: Node of Ranvier ; Na channels ; Tetrodotoxin ; Cooperativity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract 1. The steady state effects and rates of action of tetrodotoxin (TTX) on sodium current were studied in the voltage clamped frog node of Ranvier. 2. Inactivation of the sodium current was separated into fast and slow phases. Both phases were assumed to correspond to two different currents (fast and slow) flowing through fast and slow channels (Benoit et al. 1985). 3. The dose-response curve of the steady state effect of tetrodotoxin on the fast current was sigmoid. An analysis of this effect in double logarithmic coordinates gave a Hill coefficient of 1.74. 4. The rates of tetrodotoxin action on the fast current were determined by the reversible reduction of the peak current recorded at a potential (+20 mV) at which the slow current was relatively small. 5. After an initial delay, the onset of TTX effect followed an exponential function of time whose constant decreased with increasing tetrodotoxin concentrations. Expressed as the time corresponding to a reduction of 2% of the current, the delay (δt2%) increased from about 100 ms with 300 nM-TTX to about 30 s with 1 nM-TTX. 6. When tetrodotoxin was removed, the offset developed quasi-instantaneously and followed an exponential function of time whose constant was independent of the toxin concentration. 7. Both steady state and rates of tetrodotoxin effects could be fitted well if one assumed that the block of one fast channel occurred after binding of two TTX molecules to two cooperative sites.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00582567
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Chemical ideograms and molecular computer graphics (1985)
    Springer
    The visual computer 1 (1985), S. 49-63 
    Details
    ISSN: 1432-2315
    Keywords: Molecular modelling ; Computer-assisted drug design (CADD) ; Graphics language ; Molecular computer graphics (MCG) ; Chemical information systems
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract Molecular computer graphics (MCG) has become the indispensable complement of experimental chemical and biological tools and, in a way, will shape the evolution of these fields. This accelerated and popularized evolution takes root in the visual, even scenic, grasping of fundamental chemical concepts, perceived as veritable ideograms, which condense a vast amount of information with a few two- or threedimensional graphic symbols. With MCG one can carry out real computerized syntheses of chemical images. MCG is also an ideal tool through which to visualize the changes of a system as a function of time. This review article describes the potentials and advantages of structural MCG for visualizing the basic steps of important modelization concepts, particularly for handling on-line structures in information networks and in computer-assisted drug design (CADD) applications.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01901269
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Grid stage modelling functions and molecular vector graphics (1986)
    Springer
    The visual computer 2 (1986), S. 367-378 
    Details
    ISSN: 1432-2315
    Keywords: Molecular polymodelling ; POLYMOD ; 3D Grid stage ; COOBOX ; Geometric and Boolean operations ; Composite images
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract A polymodelling system (POLYMOD) is presented for varied 2D or 3D displays of chemical shapes, whether structural (molecular volumes distances, surfaces...) or electronic (molecular electrostatic potential, electron densities ...). The POLYMOD system manages reversible correspondences between calculation and representation spaces by immersing the molecules studied in a unique represetation space structured by a 3D grid box. This box, called COOBOX, defined by its point internal coordinates, is used to transform other coordinates into its own. Direct multi-slice images along thex, y, z axis provide access to a variety of derived operations around a molecular shape or set of shapes disposed in various manners. Interactive sub systems ensure Boolean operations and compare property shapes through the 3D grid. Clear separation of graphic routine and of downstream modelling programs leads to rapid and original generation of varied images (subimages, direct or composite images) which are then available for simulation strategies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01952421
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Radiation necrosis of the brain: Time of onset and incidence related to total dose and fractionation of radiation (1985)
    Springer
    Neuroradiology 27 (1985), S. 44-47 
    Details
    ISSN: 1432-1920
    Keywords: Radiation therapy ; radiation injuries ; radiation dose-interval of onset ; incidence ; brain tumor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Clinical deterioration during or after brain irradiation may be due to progression of neoplasm or radiation induced necrosis of the neoplasm and/or of normal brain tissues, or a combination of all. Eight patients with histologically documented radiation induced lesions of the brain are included in this study. The radiation therapy included the fractional schedule, group A, who received 280 to 300 rads daily, to a total dose of 4500 to 5000 rads and weekly exposure did not exceed 900 rads. Group B patients were exposed to 850 rads, daily dose on day 1, 3, 21 and 23 to a total dose of 3400 rads. The incidence of radiation induced lesions of brain was 3.4% in patients group A and 8.7% in group B patients (without) statistical significance). The median time of onset of these lesions after completion of radiation therapy was significantly shorter in group B patients (8.5 months) as opposed to group A patients (21 months).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00342516
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  • 7
    Electronic Resource
    Electronic Resource
    Cerebral vascular complication and hyperhomocysteinemia in a cystinotic uremic child (1999)
    Springer
    Pediatric nephrology 13 (1999), S. 73-76 
    Details
    ISSN: 1432-198X
    Keywords: Key words Uremia ; Homocysteine ; Cerebrovascular disease ; Thermolabile methylenetetrahydrofolate reductase variant ; Cystinosis ; Folic acid ; Vitamin B12
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  We report a 13-year-old girl with nephropathic cystinosis on chronic peritoneal dialysis who presented with two episodes of stroke. Laboratory evaluation showed severe hyperhomocysteinemia (108 µmol/l). Further testing revealed that she was homozygous for the thermolabile variant of the methylenetetrahydrofolate reductase (MTHFR) gene. Treatment with folic acid and vitamin B12 lowered plasma homocysteine to less than 20 µmol/l. No further episodes of stroke occurred over a follow-up of 12 months. Homocysteine levels should be measured in patients with chronic renal failure, since simple and safe treatment with folic acid and vitamin B12 is effective in lowering the plasma homocysteine level in patients with the thermolabile MTHFR allele.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004670050567
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    A 10-Deacetylbaccatin III Derivative: 11,12-Dihydro-7-triethylsilyl-10-deacetylbaccatin III (1995)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 51 (1995), S. 2050-2053 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108270195004616
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  • 9
    Electronic Resource
    Electronic Resource
    Structural Study of Crystalline Approximants of the Al–Cu–Fe–Cr Decagonal Quasicrystal (1995)
    Copenhagen : International Union of Crystallography (IUCr)
    Applied crystallography online 28 (1995), S. 96-104 
    Details
    ISSN: 1600-5767
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences , Physics
    Notes: Orthorhombic (O1, O2 and O3) and monoclinic (M1 and M2) phases are the crystalline approximants of the Al–Cu–Fe–Cr decagonal quasicrystal. The structures of these crystalline phases can be described using three subunits, which are derived from the O3 structure. As an example, the structural model of the O1 phase is presented in detail. This model agrees with the X-ray powder diffraction pattern and the high-resolution electron image of the O1 phase.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0021889894009714
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  • 10
    Electronic Resource
    Electronic Resource
    Study of the Relationship Between Microstucture, Fatigue and Thermal Shock Behaviour of Si〈sub〉3〈/sub〉N〈sub〉4〈/sub〉 (1997)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 132-136 (Apr. 1997), p. 615-618 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/44/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.132-136.615.pdf
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