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  • Electronic Resource  (2)
  • 1995-1999  (2)
  • 1970-1974
  • Endless-loop bougienage  (1)
  • IgE  (1)
  • 1
    ISSN: 1437-9813
    Keywords: Key words Corrosive esophageal stricture ; esophageal bougienage ; Endless-loop bougienage ; Gastrostomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The authors present a safe, conservative method of endless-loop bougienage (ELB) through the oral cavity and esophagus to a gastrostomy without general anesthesia in three children with corrosive esophageal burns treated since 1966. Esophagogastroscopy was performed to evaluate for esophagitis at an early phase after ingestion of the caustic substance. When esophageal stricture formation was recognized after subsequent conservative treatment, a feeding gastrostomy was made. A continuous string loop with plummets of progressively larger size was positioned to pass through the patient's oral cavity and esophagus to the gastrostomy. Strictures were found in the upper esophagus in two patients and in the middle and lower esophagus in one. The gastrostomy was performed 15␣months, 20 days, and 2 months after the injury, respectively, and the periods of ELB were 3, 5, and 2½␣years, respectively. The patients were able to start eating at 26, 42, and 29 months after injury, respectively. They are now 30, 18, and 17 years old, and slight dysphagia remains in patients 1 and 2. No patient developed esophageal carcinoma at the site of the corrosive stricture. Our method of ELB through the patient's oral cavity and esophagus to the gastrostomy appears to be safe, reliable, and useful. We believe that most caustic esophageal strictures in children can be treated by this conservative measure.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-069X
    Keywords: Atopic dermatitis ; Eosinophils ; FcεRI ; CD23 ; IgE
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Expression of the high affinity IgE receptor (FcεRI) on eosinophils has recently been reported. This led us to evaluate FcεRI expression on eosinophils in atopic dermatitis (AD). Double immunofluorescence stainings with an anti-FcεRI monoclonal antibody (mAb) and a polyclonal antieosinophil cationic protein (ECP) antibody were performed on lesional biopsy specimens from patients with AD and from patients with bullous pemphigoid (BP) as controls. In AD and BP lesions, 77% and 70% of eosinophils expressed FcεRI, respectively. However, the intensity of FcεRI staining in AD was much stronger than in BP, suggesting upregulation of FcεRI expression on eosinophils in AD. In addition, the eosinophils infiltrating AD lesions were stained strongly with anti-CD23 mAb and anti-IgE antibody. At the sites of mite patch testing in AD, FcεRI-, CD23- and IgE-positive eosinophils were observed to the same degree as in the lesions, and a considerable number of mite antigen-bearing eosinophils were detected. FcεRI and CD23 were both upregulated on the skin-infiltrating eosinophils in AD and bound IgE molecules.
    Type of Medium: Electronic Resource
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