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  • Electronic Resource  (6)
  • 1995-1999  (5)
  • 1915-1919  (1)
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  • Electronic Resource  (6)
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  • 1
    Electronic Resource
    Electronic Resource
    BLOOD CHEMISTRY OF WILD HARBOR PORPOISES PHOCOENA PHOCOENA (L.) (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Marine mammal science 11 (1995), S. 0 
    Details
    ISSN: 1748-7692
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Blood chemistry values were measured from 31 harbor porpoises (Phocoena phocoena) released from herring weirs in the Bay of Fundy, Canada. Sodium, phosphorus, calcium, chloride, magnesium, total protein, albumin, globulin, urea, cholesterol, serum osmolality, and alanine aminotransferase levels fell within ranges reported for captive harbor porpoises and other odontocetes. Glucose, potassium, creatine kinase, aspartate aminotransferase, hemoglobin, thyroxine, bilirubin, and alkaline phosphatase levels were generally higher than those reported for captive odontocetes. Cortisol and creatinine levels were significantly higher (P= 0.0356 and 0.0174, respectively) in porpoises that were handled for longer periods and fitted with electronic tags (mean cortisol value = 314 ± 107 nmol/L, mean creatinine value = 94 ± 14 μmol/L) than those receiving roto-tags (mean cortisol value = 222 ± 82 nmol/L, mean creatinine value = 75 ± 15 μmol/L). A more controlled study of duration of handling, time spent out of water, degree of manipulation, and method of tag attachment is required to identify which factors are responsible for the stress response.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1748-7692.1995.tb00512.x
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  • 2
    Electronic Resource
    Electronic Resource
    Linkage disequilibrium studies in multiple endocrine neoplasia type 1 (MEN1) (1997)
    Springer
    Human genetics 〈Berlin〉 100 (1997), S. 657-665 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterised by tumours of the parathyroids, pancreas and anterior pituitary. The MEN1 gene has been localised to a 2-Mb region of chromosome 11q13 by meiotic mapping studies in MEN1 families. Such studies may have a limited resolution of approximately 1 cM (i.e. 1 Mb) and we have therefore investigated 96 MEN1 families (40 British, 17 French, 12 Finnish, 7 Swedish, 7 Dutch, 7 North American, 2 Australian, 1 New Zealand, 1 German, 1 Spanish and 1 Danish) for linkage disequilibrium, in order to facilitate a finer mapping resolution. We have utilised five microsatellite DNA sequence polymorphisms from the candidate region and have accurately determined their allele sizes, which ranged from 161 bp to 272 bp. The heterozygosity and number of alleles (given in brackets), respectively, at the loci were: D11S1883 (76%, 11), D11S457 (55%, 5), PYGM (94%, 18), D11S1783 (10%, 4) and D11S449 (87%, 16). Allelic association was assessed by Chi-square 2 ×n contingency tables, by Fisher exact 2 ×n contingency tables and by a likelihood-based approach. The results of haplotype analysis revealed 91 different affected haplotypes in the 96 families, an identical affected haplotype being observed in no more than two families. These results indicate the absence of an ancestral affected haplotype. Significant linkage disequilibrium (P 〈 0.005) could be established amongst the microsatellite loci but not between the loci and MEN1 in either the total population or in any of the geographical sub-populations. The absence of linkage disequilibrium between MEN1 and the polymorphic loci is probably the result of the occurrence of multiple different disease-causing mutations in MEN1.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004390050569
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The gene for X-linked hypophosphataemic rickets maps to a 200–300 kb region in Xp22.1, and is located on a single YAC containing a putative vitamin D response element (VDRE) (1996)
    Springer
    Human genetics 〈Berlin〉 97 (1996), S. 345-352 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02185769
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  • 4
    Electronic Resource
    Electronic Resource
    Monitoring the movements of harbour porpoises (Phocoena phocoena) with satellite telemetry (1997)
    Springer
    Marine biology 130 (1997), S. 315-322 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The movements of nine harbour porpoises, Phocoena phocoena (L.), in the Bay of Fundy and Gulf of Maine were tracked using satellite telemetry. Transmitters were attached to the porpoises in August 1994 and 1995 after they were captured near Grand Manan Island at the mouth of the Bay of Fundy. Tracking periods ranged from 2 to 212 d (mean 50 ± 65 d). Porpoises exhibited a high degree of individual variation in movement patterns; five moved out of the Bay of Fundy into the Gulf of Maine. The porpoise with the longest tracking period moved extensively throughout the Gulf of Maine. These data suggest that seasonal movement patterns of individual harbour porpoises are discrete and are not temporally coordinated migrations. Porpoises that moved out of the Bay of Fundy into the Gulf of Maine did so following the 92 m isobath, which may represent an important movement corridor. The movement of porpoises from the Bay of Fundy into the Gulf of Maine supports the hypothesis that harbour porpoises from these two regions comprise a single population at risk of entanglement in both Canadian and US fisheries.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002270050251
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  • 5
    Electronic Resource
    Electronic Resource
    The gene for X-linked hypophosphataemic rickets maps to a 200–300 kb region in Xp22.1, and is located on a single YAC containing a putative vitamin D response element (VDRE) (1996)
    Springer
    Human genetics 〈Berlin〉 97 (1996), S. 345-352 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The location of the HYP gene, which determines X-linked hypophosphataemic rickets, has been refined considerably by linkage analysis, and three new microsatellite primers isolated, Cap32 (DXS7473), Cap29 (DXS7474) and 7v2 (DXS7475). The locations of four other markers have also been determined (DXS1226, AFMa176zb1, AFMa152wc5, and AFM346azc1). Markers Cap29 and Cap32 are the closest distal markers to the gene with z max = 11.93, θ max = 0.018, and z max = 12.03, θ max = 0.015 respectively. Both Cap29 and Cap32 are proximal to DXS365 and AFMa176zb1, as deduced by screening non-chimaeric yeast artificial chromosomes (YACs) from a contig spanning the HYP gene. A single crossover places AFMa176zb1 distal to the disease gene. There are no recombinations between 7v2 and HYP (z max = 12.9, θ max = 0.0), or between 7v2 and adjacent markers Cap32, Cap29, AFMa176zb1, DXS1683 and DXS365. However screening of YAC clones encompassing the HYP gene and also P1 clones localises 7v2 distal to Cap29 and Cap32, and proximal to DXS443. Marker DXS1226 is placed outside the region containing the gene, and is located proximal to DXS274 as confirmed by a crossover for this marker and DXS41 against HYP, and its presence on YAC 83BO5. Genetic mapping of CEPH pedigrees, and screening of YACs places AFMa152wc5 and AFMa346zc1 between DXS1683 and DXS1052. The following gene marker map presents the best order for the HYP region: Xptel-DXS43-DXS999-DXS443-(DXS365/DXS7475/ AFMa176zb1)-(DXS7474/DXS7473)-HYP-DXS1683-(AFMa152wc5/AFMa346zc1)-DXS1052-DXS274-(DXS41/DXS1226)-Xcen. The distance between the cluster of distal flanking markers Cap29 (DXS7474), Cap32 (DXS7473), and DXS1683 is approximately 300 kb, as deduced from physical map data from a YAC contig spanning the gene. Thus the gene for HYP is contained within a single YAC (900AO472). Of further interest, is the location of a putative vitamin D response element (VDRE) on this YAC.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004390050048
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  • 6
    Electronic Resource
    Electronic Resource
    Die kolorimetrische Bestimmung des Kohlenstoffs (1919)
    Springer
    Fresenius' Zeitschrift für analytische Chemie 58 (1919), S. 206-211 
    Details
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01675938
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    Paper (German National Licenses)
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