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  • Electronic Resource  (2)
  • 1995-1999  (2)
  • Cyclosporine G  (1)
  • bioaccumulation  (1)
  • Distance matrix
  • 1
    ISSN: 1432-198X
    Keywords: Cyclosporine G ; Cadaveric transplantation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Cyclosporine G (OG 37-324) reportedly is an efficacious immunosuppressant with less nephrotoxicity than cyclosporine A. This is a prospective randomized double-blinded trial comparing cyclosporine G and cyclosporine A in cadaveric renal transplantation. Patient and graft survival, as well as major infectious complications, were not different between the two groups. Objective parameters of renal function, including serum creatinine, creatinine clearance, and inulin clearance, were routinely performed. These generally demonstrated less nephrotoxicity in those patients treated with cyclosporine G compared with cyclosporine A. Minor elevations of alanine aminotransferase were noted in the cyclosporine G-treated patients but this was not associated with acute morbidity. Overall, cyclosporine G appears to be equally as effective as cyclosporine A, but demonstrated notably less nephrotoxicity.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Environmental geochemistry and health 17 (1995), S. 119-126 
    ISSN: 1573-2983
    Keywords: Metal retention ; speciation ; surface flow ; subsurface flow ; bioaccumulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Medicine
    Notes: Abstract The ability of surface flow and subsurface flow simulated wetlands to remove heavy metals from a NaCI-enriched wastewater was examined, employing bulrush (Scirpus validus) and cattail (Typha angustifolia) plants, and two organically amended substrates (mixtures of mushroom compost and leaf litter,with topsoil) with a limestone liner. A simulated wastewater solution containing Cd, Cr, Cu, Fe, Mn, Ni, Pb and Zn as chloride salts was added to the wetlands at a rate of 0.3 l h−1. During 12 weeks of surface flow, Fe was retained most efficiently (74%), and Mn the least (24%). Most metal retention occurred in residual forms, primarily in the upper 5 cm of the substrate. A subsequent 10 week subsurface flow treatment exhibited greater removal efficiencies for all metals, probably due to increased contact with the highly buffered lower substrate. During both treatments, bioaccumulation occurred in plants, but accounted for a very small portion of the total metal removal. Plant species did not significantly influence wetland performance with respect to metal retention. Substrate type did not affect removal efficiency for most metals, but did influence the forms of the metals retained in the wetland.
    Type of Medium: Electronic Resource
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