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  • Electronic Resource  (10)
  • 1970-1974  (10)
  • 1
    Electronic Resource
    Electronic Resource
    ATP synthesis by mitochondria of brain synaptosomes (1974)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 23 (1974), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1974.tb10761.x
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  • 2
    Electronic Resource
    Electronic Resource
    THE EFFECT OF γ-AMINOBUTYRIC ACID ON BRAIN MITOCHONDRIAL ATP SYNTHESIS (1974)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 23 (1974), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: —Rat brain mitochondrial ATP synthesis was studied by measuring labeled orthophosphate incorporation into ADP to form ATP. GABA stimulates ATP synthesis, and this effect requires glutamate since with GABA alone little ATP is formed. The significance of this effect by GABA is unclear, but the mechanism may relate to induction of conformational change or chelation of cation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1974.tb04396.x
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  • 3
    Electronic Resource
    Electronic Resource
    Nitric Oxide Reduction on Copper-Nickel Catalysts (1974)
    s.l. : American Chemical Society
    Industrial and engineering chemistry 13 (1974), S. 61-64 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/i360049a012
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  • 4
    Electronic Resource
    Electronic Resource
    Effect of lead on oxidation activity of copper oxide-alumina catalyst (1972)
    s.l. : American Chemical Society
    Environmental science & technology 6 (1972), S. 239-242 
    Details
    ISSN: 1520-5851
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/es60062a004
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  • 5
    Electronic Resource
    Electronic Resource
    Growth and metabolic changes in weanling rats with lesions in the dorsomedial hypothalamic nuclei (1972)
    Springer
    Experimental brain research 15 (1972), S. 424-429 
    Details
    ISSN: 1432-1106
    Keywords: Hypothalamus ; Metabolism ; Growth ; Dorsomedial Nucleus body composition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary When compared with sham-operated ad libitum-fed controls, weanling rats with lesions primarily destroying the dorsomedial hypothalamic nuclei (DMNL rats) showed reduced ponderal and linear growth and food intake, normal carcass fat but increased carcass protein. Among the metabolic parameters measured, DMNL rats showed only decreased incorporation of palmitate into epididymal fat pad phospholipid and triglyceride. When sham-operated controls were pair-fed with DMNL rats, they showed growth changes almost identical with those observed in lesioned rats. However, their carcass protein was lower than both that of the lesioned rats and the ad libitum-fed controls. Metabolically, the sham-operated, pair-fed controls showed decreased incorporation of palmitate into triglyceride of epididymal fat pads and decreased oxidation of glucose and increased incorporation into total lipid of the diaphragm. When previous data on growth hormone, insulin, triglyceride and cholesterol are compared with the present findings it is suggested that dorsomedial lesions cause a subcaloric-type dwarfism that does not involve adenohypophyseal secretions and their target organs affecting growth.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00234127
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  • 6
    Electronic Resource
    Electronic Resource
    Normal plasma growth hormone levels in growth-retarded weanling rats with dorsomedial hypothalamic lesions (1973)
    Springer
    Experimental brain research 18 (1973), S. 374-382 
    Details
    ISSN: 1432-1106
    Keywords: Growth retardation ; Hypothalamus ; Dorsomedial lesions ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Weanling rats received bilateral electrolytic lesions destroying the areas of the ventromedial (VMN) and dorsomedial (DMN) hypothalamic nuclei, respectively. Trunk blood was collected at sacrifice (Experiment 1 and 2∶ 31 days, Experiment 3∶ 14 days) for the determination of plasma growth hormone (GH) by radioimmunoassay. Rats with DMN lesions showed consistently normal to slightly elevated plasma GH levels while animals with VMN lesions showed significantly reduced plasma GH levels. Linear growth was reduced by both types of hypothalamic lesions but body weight gains and food intake were reduced only in the DMN lesioned rats. Carcass fat was greatly elevated in VMN lesioned rats, moderately elevated in one experiment in the DMN animals and normal in another experiment. These data confirm a previous hypothesis that growth retardation in DMN rats is not due to low circulating GH level but rather represents a hypocaloric-type dwarfism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00239106
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  • 7
    Electronic Resource
    Electronic Resource
    Participation of the dorsomedial hypothalamic nucleus in the “feeding center” and water intake circuitry of the weanling rat (1970)
    Springer
    Journal of neural transmission 31 (1970), S. 387-398 
    Details
    ISSN: 1435-1463
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Präzise elektrolytische Läsionen wurden in den dorsomedialen (DMNL) und ventromedialen (VMNL) hypothalamischen Kernen von abgesetzten Ratten placiert, um ihren Einfluß auf Futter- und Wasseraufnahme, Körperwachstum und Zusammensetzung zu studieren. Läsionen in den DMN hatten Hypophagie, Hypodipsie und gehemmtes Körperwachstum zur Folge, sowohl im Vergleich zu den Kontrollen als auch den VMNL-Tieren. Die DMNL-Tiere enthielten mehr Körperwasser und fettfreie Körpermasse, aber weniger Fett als die VMNL-Ratten. Der beschriebene Effekt wurde auch in DMNL-Ratten beobachtet, welche Läsionen von nur 2.5 mC erhalten hatten, während die in den VMNL-Tieren beobachteten Veränderungen nach solchen kleinen Läsionen nicht mehr augenscheinlich waren. Die Ergebnisse zeigen, daß die DM-Kerne, wenigstens in der abgesetzten Ratte, an der Regulation von Futter- und Wasseraufnahme teilnehmen und daß dieses neuronale Gebiet scharf begrenzt ist.
    Notes: Summary Precise electrolytic lesions were placed in the dorsomedial (DMNL) and ventromedial (VMNL) hypothalamic nuclei of weanling rats to study the effect on food and water intake, body weight and length and body composition. Lesions in the DMN consistently resulted in hypophagia, hypodipsia and decreased ponderal and linear growth, both when compared with VMNL rats and with sham-operated controls. The DMNL rats contained more carcass water and lean body mass but less fat than the VMNL rats. The lesion effect persisted in the DMNL rats even after placement of minute lesions of 2.5 mC, while such lesions failed to elicit the changes found with larger lesions in the VMNL rats. The data show that the DMN, at least in the weanling rat, appear to be part of the “feeding center” and water intake circuitry. They also show the minuteness of the area involved and its sharp functional and anatomical delineation from the VMN.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02312740
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  • 8
    Electronic Resource
    Electronic Resource
    Localization in the ventromedial hypothalamic nuclei of an area affecting plasma triglyceride and cholesterol levels (1971)
    Springer
    Journal of neural transmission 32 (1971), S. 90-103 
    Details
    ISSN: 1435-1463
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In drei Experimenten wurden elektrolytische Läsionen im vorderen bzw. medialen, dorsalen und hinteren Gebiet des Hypothalamus der weiblichen abgesetzten Ratte plaziert, um den Locus zu bestimmen, dessen Zerstörung Hypertriglyceridämie und Hypercholesterinämie verursacht. In einem weiteren Experiment wurden Läsionen verschiedener Größe im ventromedialen Hypothalamus plaziert, um die Ausdehnung der verantwortlichen Nervenmasse zu definieren. Nur Läsionen, welche hauptsächlich den ventromedialen hypothalamischen Kern zerstören, verursachen bedeutende Erhöhungen von Triglyceriden und Cholesterinspiegeln. Kleine Läsionen, welche auf das mittlere Gebiet des ventromedialen Kernes beschränkt sind, verursachen die erwähnten Erscheinungen nicht. Mit größer werdendem Läsionsherd werden die Änderungen der Plasmalipide aber größer. Die Ergebnisse weisen darauf hin, daß die ventromedialen hypothalamischen Kerne und ihr unmittelbares Grenzgebiet den Fettstoffwechsel beeinflussen.
    Notes: Summary In three experiments exploratory lesions were placed in anterior, medial, dorsal and posterior hypothalamic areas of weanling female rats to determine the localization and the extent of the area affecting plasma triglyceride and cholesterol levels. In another experiment, lesions of various sizes were placed in the ventromedial hypothalamic area to define the size of the lesions necessary to elevate plasma triglyceride and cholesterol levels. Three or more weeks after the hypothalamic operation, trunk blood was obtained after decapitation. Only lesions destroying primarily the ventromedial hypothalamic nuclei resulted in significant elevations of both lipid fractions. Small lesions, confined to the medial area of the VMN in antero-posterior respect did not produce the above alterations, but with increasing lesion size significant positive correlations between lesion size and plasma lipid levels were evident. The data suggest that the ventromedial hypothalamic nuclei are a hypothalamic site which influences lipid metabolism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02310042
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  • 9
    Electronic Resource
    Electronic Resource
    Peak aortic and carotid flow acceleration in anesthetized dogs (1974)
    Springer
    Annals of biomedical engineering 2 (1974), S. 183-193 
    Details
    ISSN: 1573-9686
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract Peak carotid and peak aortic flow acceleration were compared during a variety of cardiovascular interventions in seven acutely instrumented anesthetized (pentobarbital 30 mg/kg, iv) dogs. Flow velocity, recorded with electromagnetic sensors, was processed electronically to give acceleration and the ratio of peak carotid to peak aortic acceleration on a beat-by-beat basis. Occlusion of the left coronary artery, occlusion of the superior vena cava and intravenous administration of sodium bicarbonate and propranolol caused both peak carotid and peak aortic flow acceleration to decrease with little or no change in their ratio. Breathing 100% oxygen and iv infusions of metaraminol, levarterenol, isoproterenol, and acetyl choline and iv injection of serotonin, papaverine, and deslanoside increased peak carotid and peak aortic flow acceleration. The ratio of peak carotid to peak aortic acceleration did not change greatly except with isoproterenol, papaverine, and acetyl choline, when peak carotid flow acceleration increased more than peak aortic flow acceleration causing an increase in their ratio. Intravenous infusion of trimethaphan camphorsulfonate and injection of histamine caused peak carotid flow acceleration to increase and peak aortic flow acceleration to decrease with an increase in their ratio. Peak carotid flow acceleration may be of use as an indirect measure of myocardial mechanical performance except during potent peripheral vasodilation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02368489
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  • 10
    Electronic Resource
    Electronic Resource
    Neuartige Abbaureaktionen von Halogenmethyl-Derivaten des Bis(diacetyldioximato)kobaltsDiese Arbeit wurde durch Grant 1-RO 1 ES 00325-01 des US Department of Health, Education and Welfare unterstützt. (1971)
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 83 (1971), S. 849-850 
    Details
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ange.19710832108
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