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  • Electronic Resource  (3)
  • 1990-1994  (3)
  • Anal stricture  (1)
  • Anorectal myectomy  (1)
  • Laminin  (1)
Material
  • Electronic Resource  (3)
Years
  • 1990-1994  (3)
Year
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Diseases of the colon & rectum 33 (1990), S. 566-572 
    ISSN: 1530-0358
    Keywords: Restorative proctocolectomy ; J-pouch ; W-pouch ; Anal stricture ; Proctography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Videoproctography was performed in 40 patients after restorative proctocolectomy to evaluate pouch emptying, anopouch angle, and pelvic floor movement in relationship to functional outcome. Results were compared between the two different pouch designs tested and a control group of 26 patients who had an intact rectum. There was no difference in emptying between the two pouch designs or compared with the control subjects. Emptying did not influence either the frequency of defecation or patient soiling rate. The presence of an anal stricture was associated with poor emptying in each case in the pouch group. Anorectal angle was no different between the different pouch designs or compared with the control group at rest, during pelvic floor contraction, or attempted defecation. A similar finding was obtained with anorectal angle position and movement during pelvic floor contraction and attempted defecation in both pouch design groups and when compared with normal rectum. This study shows that the only factor that is consistently associated with poor pouch emptying is the presence of an anal stricture.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Diseases of the colon & rectum 33 (1990), S. 795-797 
    ISSN: 1530-0358
    Keywords: Constipation ; Anorectal myectomy ; Aganglionosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Anorectal myectomy has been shown to provide clinical benefit to patients with outlet obstruction. Long-term results of anorectal myectomy have been evaluated in 57 patients operated on between February 1984 and February 1988 with a median follow-up of 24 months. Overall improvement was recorded in only 31 percent of patients. Spontaneous evacuation without the need for laxatives was recorded in only 11 patients (19 percent), while 38 (67 percent) had no functional improvement. Results were independent of preoperative colonic transit or histologic evidence of aganglionosis. Anorectal myectomy identified aganglionosis in 23 percent of patients with chronic constipation, but there was minimal long-term benefit from the procedure.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-0533
    Keywords: Serotonin ; Dystrophin ; Duchenne muscular dystrophy ; Type IV collagen ; Laminin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Degenerating and regenerating muscle fibers, in serotonin-induced myopathy (SM) of rats, were investigated histochemically, immunohistochemically and electron microscopically with polyclonal antibodies against dystrophin, type IV collagen and laminin. The myopathy produced was characterized by grouping of degenerating and regenerating muscle fibers, and degeneration of capillary endothelial cells. Dystrophin disappeared in an early stage of muscle degeneration and reappeared in an early stage of regeneration. On the other hand, type IV collagen and laminin were well preserved throughout the degeneration and regeneration processes, even on the shrunk and wrinkled basement membrane of empty muscle fibers after phagocytosis. Muscle fiber regeneration was completed within each tube of the preserved basement membrane through the fusion of myoblasts derived from satellite cells of single necrotic fibers, myotubes already being visible on the 1st or 2nd day of regeneration on light microscopy. These small regenerating myotubes did not fuse with each other at all. The findings in the present experimental SM study are compatible with those in Duchenne muscular dystrophy, especially at the preclinical stage.
    Type of Medium: Electronic Resource
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