ISSN:
1432-1920
Keywords:
Cerebral blood flow
;
Cerebral oxygen utilisation
;
Positron emission tomography
;
Cerebral tumours
;
Cerebral oedema
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Regional cerebral blood flow and oxygen utilisation have been studied in 8 patients with brain tumours using continuous inhalation of C15O2 and 15O2 and positron emission tomography. The methods used to analyse the regional cerebral pathophysiology are presented. A relative uncoupling between oxygen consumption and blood flow was observed in all tumours as indicated by a decreased regional fractional extraction of oxygen (rOER). This suggests that a major proportion of these tumours had sufficient blood supply to meet oxygen metabolic demand. A decrease of blood flow in grey matter was found both in the affected and contralateral hemispheres of the brain. Matched reductions of flow and oxygen utilisation were observed in oedematous tissue.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00367239
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