ISSN:
0570-0833
Keywords:
Polysaccharides
;
Nucleosides
;
Nucleic acids
;
DNA replication
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Compounds containing free amino, hydroxyl or carbonyl groups can be activated by reaction with polyphosphate ester. If the compounds contain a second functional group, polycondensations are possible; e.g. amino acids → polypeptides, carbohydrates → polysaccharides, nucleotides → polynucleotides. In the presence of polyadenylic acid, polymerization of uridylic acid is speeded up tenfold. This mutual effect of complementary nucleotide strands constitutes the experimental basis for a hypothesis concerning the terrestrial origin of systems capable of self-reproduction.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/anie.196200011
Permalink