Electronic Resource
Springer
Journal of molecular medicine
66 (1988), S. 475-481
ISSN:
1432-1440
Keywords:
Mexiletine
;
Pharmacokinetics
;
Drug monitoring
;
Antiarrhythmic therapy
;
Therapeutic efficacy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Pharmacokinetics of the antiarrhythmic agent mexiletine were found to be highly variable. Ineffective or toxic doses can be avoided by monitoring mexiletine concentrations in patients plasma. However, the success of antiarrhythmic therapy is mainly determined by the severety of the underlying disease. Therefore, the efficacy of treatment with mexiletine should be controlled by Holter monitoring.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01876168
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