ISSN:
1432-1041
Keywords:
metaclazepam
;
benzodiazepines
;
(KC-2547)
;
N-desmethyl-methaclazepam KC-3755)
;
pharmacokinetics
;
old and young volunteers
;
side-effects
;
age effect
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary A single-centre, open, Phase I-study comparison of the pharmacokinetics of a single dose of metaclazepam 10 mg, a new 1,4-benzodiazepine has been done in 10 older and 20 younger volunteers. No important age-related effect was found on the kinetics of metaclazepam or its N-desmethyl derivative, the principal metabolite in man.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00547431
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