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  • Electronic Resource  (5)
  • 1980-1984  (5)
  • electro-oculogram (EOG)  (3)
  • Diamox response  (2)
  • Clinical feature in Japan  (1)
  • (Mouse osteoblast cells)
  • Enzyme immunoassay
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Urological research 11 (1983), S. 235-238 
    ISSN: 1434-0879
    Keywords: Urachal carcinoma ; Clinical feature in Japan ; Comparison with Western countries
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Carcinoma of the urachus is not as uncommon as previously considered. 157 cases diagnosed to have urachal carcinoma collected from the Japanese literature were reviewed and the findings were compared with those reported in the English literature. The incidence of the disease ranges from 0.55 to 1.2% of bladder tumours in Japan in contrast with 0.07 to 0.70% in the Western countries. Males accounted for 72% of the patients. The highest age incidence occurred between fifth and sixth decades. The commonest presenting symptom was haematuria (71%). Adenocarcinoma accounted for 88% of the tumours most being mucous producing. Various treatment modalities were used, however, and the prognosis remained uniformly poor. An analysis of 66 patients with known outcome revealed an overall 5-year survival rate of 6%. The authors conclude that the disease tends to have a relatively higher incidence in Japan (Far East). When comparing the parameters of sex, age, presenting symptom, histopathology, treatment and prognosis, urachal carcinoma appears to have the same characteristics in the Far East as in Western countries.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-2622
    Keywords: retinal detachment ; standing potential ; hyperosmolarity response ; light peak/dark trough (L/D) ratio ; electro-oculogram (EOG)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The hyperosmolarity response of the ocular standing potential was recorded in unilateral rhegmatogenous retinal detachment (8 eyes) and in the fellow ‘healthy’ eye (8 eyes). The hyperosmolarity response was greatly suppressed (M-4 SD: M and SD indicate respectively the mean and the standard deviation in normal subjects) in all affected eyes (p 〈 0.005), and slightly abnormal in 2 fellow eyes. The L/D ratio was normal in 2 affected eyes and in all fellow eyes. The hyperosmolarity response in the affected eyes was still greatly suppressed 14 months after successful surgical treatment.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1573-2622
    Keywords: retinal pigment epithelium (RPE) ; standing potential ; hyperosmolarity response ; retinitis pigmentosa ; central and pericentral retinitis pigmentosa ; pigmented paravenous retinochoroidal atrophy ; fundus albipunctatus ; Stargardt's disease ; fundus flavimaculatus ; light peak/dark trough (L/D) ratio ; Diamox response ; electro-oculogram(EOG)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The hyperosmolarity response of the standing potential was recorded in retinitis pigmentosa (20 eyes), central (pericentral) retinitis pigmentosa (4 eyes), pigmented paravenous retinochoroidal atrophy (2 eyes), fundus albipunctatus (8 eyes), and Stargardt's disease (or fundus flavimaculatus) (14 eyes). The light peak/dark trough ratio (the L/D ratio) and the Diamox response were also determined. The hyperosmolarity response was greatly suppressed (less than M-4SD; M and SD indicate respectively the mean and the standard deviation in normal control subjects) in all examined eyes with retinitis pigmentosa (20 eyes) including retinitis pigmentosa sine pigmento (8 eyes), central (pericentral) retinitis pigmentosa (4 eyes), and pigmented paravenous retinochoroidal atrophy (2 eyes). The L/D ratio was larger than 1.26 (M-2.5 SD) in the half of the eyes with the above-described diseases. The hyperosmolarity response was abnormal (less than M-2 SD) in 4 of 8 eyes with fundus albipunctatus. The L/D ratio was normal in all 8 eyes. The hyperosmolarity response was abnormal (less than M-2 SD) in all 14 eyes with Stargardt's disease or fundus flavimaculatus. The L/D ratio was abnormal in 5 of these 14 eyes. The hyperosmolarity response was more frequently abnormal than the L/D ratio in the chorioretinal dystrophies mentioned above, and hence is useful particularly for early diagnosis of these disorders.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1573-2622
    Keywords: diabetic retinopathy ; standing potential ; hyperosmolarity response ; Diamox response ; light peak/dark trough (L/D) ratio ; electro-oculogram (EOG)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The hyperosmolarity response, a drug-induced response from the retinal pigment epithelium, was recorded in diabetic retinopathy. The hyperosmolarity response was occasionally abnormal at the pre-retinopathic stage and at the first stage of retinopathy by Scott classification. The response was frequently abnormal at the second and third stages of retinopathy. The hyperosmolarity response is useful for early diagnosis of pigment epitheliopathy in diabetes.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1573-2622
    Keywords: retinal pigment epithelium (RPE) ; ocular standing potential ; hyperosmolarity response ; electro-oculogram (EOG)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The standing potential of the eye is decreased by intravenous administration of hypertonic solutions. This hyperosmolarity-induced response has been recorded in normal subjects by the use of electro-oculography (EOG) in the dark. An intravenous administration of Fructmanit® (1.4 × 103 mOsmol) (150 ∼ 500ml, 2.37 ∼ 9.70ml/kg, 0.08 ∼ 0.36 ml/kg/min) was used to evoke the hyperosmolarity response. The amplitude of the response was expressed in percentage, V0 − Vmin/V0 × 100, where V0 is the base value of the EOG before administration of the hypertonic solution and Vmin is a minimum EOG amplitude after administration. The distribution of the amplitude of the hyperosmolarity response was approximated by the normal distribution in normal subjects. The minimum, the maximum, the mean and the standard deviation of the amplitude of the hyperosmolarity response were respectively 34.2%, 52.3%, 42.6% and 4.6% in normal subjects. The normal range of the hyperosmolarity response would be 33.4 ∼ 51.8% (M ± 2SD). The hyperosmolarity response, which originates mainly in the retinal pigment epithelium, is a useful new quantitative and specific test of the activity of the retinal pigment epithelium in clinical practice.
    Type of Medium: Electronic Resource
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