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  • Electronic Resource  (2)
  • 1980-1984  (2)
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  • Electronic Resource  (2)
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  • 1
    Electronic Resource
    Electronic Resource
    Adenosine mediates a slow hyperpolarizing synaptic potential in autonomic neurones (1984)
    [s.l.] : Nature Publishing Group
    Nature 311 (1984), S. 62-65 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Vesical parasympathetic ganglia isolated from the surface of the urinary bladder were placed in a chamber superfused with oxygenated (95% O2/5% CO2) Krebs' solution of the following composition (mM): NaCl, 117; KC1, 4.7; MgCl2, 1.2; CaCl2, 2.54; NaH2P04, 1.19; NaHCO3, 25 and glucose, 11. We ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/311062a0
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    A kinetic analysis of the facilitatory action of adrenaline (1982)
    Springer
    Pflügers Archiv 392 (1982), S. 304-306 
    Details
    ISSN: 1432-2013
    Keywords: Na+−K+ pump ; 22Na+-efflux ; Adrenaline ; Frog skeletal muscle
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The22Na+-efflux from skeletal muscle cells of frog (Rana nigromaculata) was measured in Ringer solutions containing different concentrations of K+ (0.1 to 30 mM). The effects of adrenaline (30 μM) and ouabain (10 μM) on the22Na+-efflux were investigated for the purpose to clarify the mechanism of the facilitatory effect of adrenaline on Na+−K+ pump. The rate coefficient for the ouabain-sensitive22Na+-efflux increases with increasing extracellular K+ concentrations and adrenaline potently facilitates these rate coefficients. On the basis of Michaelis-Menten type kinetics assumed for the reaction between pump site and extracellular K+, it is concluded that adrenaline decreases the dissociation constant (Km), and increases the maximum Na+-efflux.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00584316
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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