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  • Digitale Medien  (2)
  • 1980-1984  (2)
Materialart
  • Digitale Medien  (2)
Erscheinungszeitraum
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  • 1
    ISSN: 1432-1106
    Schlagwort(e): Metabolism ; Intracerebellar nuclei ; Inferior olive
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Metabolic activity of the intracerebellar nuclei during cryoinactivation of the inferior olive was studied in the anaesthetized rat by using the 14C-2-deoxyglucose method. Single unit recording of Purkinje cells was simultaneously monitored in the cerebellar cortex. Local inactivation in the inferior olive resulted in regional suppression of complex spike discharges in the cerebellar cortex. An increased metabolic activity was observed in the cerebellar nuclei contralateral to the cryoinactivation site correlating the somatotopically arranged olivo-cerebello-nuclear circuit. This increase was shown to be due specifically to inactivation of the inferior olive, since it was not obtained in a rat in which the inferior olive was previously destroyed by neurotoxic doses of 3-acetylpyridine. The results are interpreted as being due to an increased presynaptic activity of the terminals of the Purkinje cells which fire simple spikes at high rates after climbing fibre deafferentation.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Experimental brain research 42 (1981), S. 215-218 
    ISSN: 1432-1106
    Schlagwort(e): Inferior olive ; Climbing fibres ; Cerebellum ; Throphic action ; Motor learning
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Following an almost total chemical lesion of the inferior olive, the inhibitory control of the cerebellar Purkinje cells upon their target neurones, mainly in Deiters nucleus, remains practically unchanged. This result is at variance with some recent findings having important implications in the cerebellar theories of motor learning.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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