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  • Electronic Resource  (6)
  • 1980-1984  (6)
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  • Electronic Resource  (6)
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  • 1
    Electronic Resource
    Electronic Resource
    Continuous Synthesis of Glycerides by Lipase in a Microporous Membrane Bioreactor (1984)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 434 (1984), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1984.tb29892.x
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  • 2
    Electronic Resource
    Electronic Resource
    A horizontal packed-bed bioreactor to reduce CO2 gas holdup in the continuous production of ethanol by immobilized yeast cells (1981)
    Springer
    Applied microbiology and biotechnology 13 (1981), S. 96-101 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary CO2 gas, evolved during alcohol fermentation using immobilized yeast, causes several undesirable problems in a packed-bed bioreactor installed vertically as it increases the dead space and causes hydrostatic pressure. In order to reduce this “CO2 gas phase effect” which lowers the efficiency of ethanol production, a shallow, horizontal packed-bed bioreactor has been developed with a free space above the gel bed. The horizontal packed-bed bioreactor was 1.5 times more productive than the vertical packed-bed bioreactor when operated continuously. Yeast cells immobilized in calcium alginate gel reached a steady state much quicker than those immobilized in polyacrylamide gels. In the horizontal packed-bed bioreactors, calcium alginate gel was also superior to polyacrylamide gel with respect to ethanol productivity. The profiles of both glucose and ethanol concentrations against axial sampling sites suggested that the horizontal packed-bed bioreactor was similar to a plug flow reactor. The mean gel size gradually increased upstream (1.9 mm to 3.3 mm). With the economic production of ethanol in view, the published data on different continuous alcohol production processes have been compared by plotting their productivities (y-coordinate) against the ethanol concentrations in the effluents (x-coordinate) for the dilution rate or space velocity at which the yield of ethanol from glucose was 95%. The horizontal packed-bed bioreactor has a very high performance which makes this bioreactor promising for the economic production of ethanol.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00499695
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Interrelationship among specific rates of cell growth, substrate consumption, and metabolite formation in some simple microbial reactions producing primary metabolites (1981)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 23 (1981), S. 1373-1387 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Applying the carbon balance principle, the interrelationship between ν = μ/Y + m (μ is the specific growth rate of microorganism, v is the specific substrate consumption rate) and π = Aμ B (Luedeking-Piret eqyuation, π is the specific metabolite formation rate) has been established for three types of simple microbial reactions. Equations for the kinetic parameters A and B have been proposed for each of the three types of microbial reactions, Expresses in terms of γx, γs and γp (carbon contents of dry cell, mass, major carbon energy source, and metabolite) as well as the parameters Y and m. Values of both A and B calculated from the proposed equations were compared with their experimental data for lactic acid fragmentation, aerobic SCP production, and alcohol fermentation. The estimated values agreed with the observed ones with reasonably small deviations.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260230616
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  • 4
    Electronic Resource
    Electronic Resource
    The minimum-sized ideal reactor for continuous alcohol fermentation using immobilized microorganism (1982)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 24 (1982), S. 2731-2737 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260241211
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  • 5
    Electronic Resource
    Electronic Resource
    Application of porous teflon tubing method to automatic fed-batch culture of microorganisms. I. Mass transfer through porous teflon tubingThis part was presented at the annual meeting of the Society of Chemical Engineers, Japan, on April 4, 1979. (1981)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 23 (1981), S. 2493-2507 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: For the purpose of a rational design for an automatic feedback control system incorporating a porous Teflon tubing sensor in semibatch culture, steady-state mass-transfer characteristics of tubing sensors have been investigated theoretically and experimentally, and also dynamic responses have been studied experimentally. A distributed mathematical model for steady-state diffusion has been solved numerically and its solution has been shown as useful for the sensor design. The overall mass-transfer resistance of radial diffusion has been shown to be the sum of external liquid-film mass-transfer resistance and membrane diffusion resistance. The steady-state experiments using ethanol dissolved in water revealed that its transfer into the tubing was controlled by the molecular diffusion within the tubing-wall membrane. Oxygen transfer from external water into the tubing was shown experimentally to be controlled by the liquid-film resistance outside the tubing. In general, the radial mass transfer of a substance having a small Henry's constant is controlled by the liquid-film resistance.The response of the tubing sensor-detector-recorder system for the stepwise addition of ethanol into the external water could not be represented by a simple combined system of the first-order delay with lag time. The responses depend on the characteristics of the tubing as well as flow rate of the carrier gas, etc., but they were quite excellent in all cases (e.g., 90% in 20 s).
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260231109
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Application of porous teflon tubing method to automatic fed-batch culture of microorganisms II. Automatic constant-value control of fed substrate (ethanol) concentration in semibatch culture of yeastThis part was presented at 6th International Fermentation Symposium, University of Western Ontario, London, Canada, on July 25, 1980 (1981)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 23 (1981), S. 2509-2524 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: An automatic feedback control system incorporating a porous Teflon tubing sensor was developed and a strain of yeast was cultivated semibatchwise in mineral salt medium by feeding pure ethanol as the sole carbon source. In the control system, The ethanol concentration was continuously measured by the porous Teflon tubing sensor combined with a flame ionization detector, and its output signals were furnished to an automatic feed controller which controlled an ethanol feed pump so that deviations from the set level of ethanol concentration might be corrected. The controller was constructed on the basis of proportional-differential negative feedback control of which the proportional sensitivity and differentiation constants were estimated from the dynamic mass balance of ethanol. Precise measurement of temperature and compensation of the detector output signals for temperature fluctuations of culture broth were necessary to achieve good control. Cultivation experiments were carried out with three levels of concentrations: 102, 103, and 104 ppm. The relative deviations of the concentrations were less than ±0.5% for the 103- and 104- ppm levels but a little offset arose for the 102-ppm levels. The growth of cells was at first exponential and then almost linear when the dissolved oxygen concentration dropped considerably.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260231110
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