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  • Electronic Resource  (2)
  • 1975-1979  (2)
  • Chemistry  (1)
  • insulin disappearance rate  (1)
  • GTP-binding protein
  • Interdigitated gel phase
  • Osmoelastic coupling
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  • Electronic Resource  (2)
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  • 1
    ISSN: 1432-0428
    Keywords: Insulin delivery rate ; insulin secretion in man ; glucose ; tolbutamide ; insulin disappearance rate ; biphasic insulin secretion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Serum insulin response to a single bolus of IV glucose or tolbutamide was measured in eight healthy subjects. Insulin disappearance rate was assessed by deconvolution from the serum insulin levels, using the measured insulin disappearance rate. The mean rate constant of insulin disappearance was 0.238±0.005 min−1 (mean±SEM). Basal insulin delivery rate was 8.0 to 9.0 mU/min and the delivery rate following glucose injection (0.5 g/kg body weight) showed a biphasic response, whereas that after tolbutamide injection (15.6 mg/kg body weight), a monophasic response. After glucose injection, 1.7±0.3 U of insulin was delivered during the first phase (0–10 min) and 5.6±1.6 U during the second phase (11–60 min). After tolbutamide injection, 1.5±0.3 U of insulin was delivered during the first 10 min. Between 11 and 40 min, 1.6±0.5 U of insulin was delivered. The results thus confirm and also quantitate biphasic insulin secretion after a bolus of glucose with a monophasic response after tolbutamide. The method is suitable for studies of the insulin secretogogues in man.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 17 (1977), S. 410-413 
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Thermally-reacted poly(methacrylamide) degrades under high-energy irradiation. It has a sensitivity of 2-3 × 10-7 C/cm2 when exposed to 10 KV electrons. The resist is thermally stable to 330°C and has a high glass transition temperature, 180 200°C. It may be used for the lift-off process and ion-milling.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
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