ISSN:
1434-0879
Keywords:
Haematogenous pyelonephritis
;
Urinary bacterial count
;
Bacterial count of renal tissue
;
Histopathological findings
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary In 22 rabbits it was possible to produce haematogenous pyelonephritis of the left kidney by means of a 48-hour ligature of the left ureter and a single intravenous injection of 1 ml of a pseudomonas aeruginosa suspension with 1011 living bacteria. In the follow-up study the antibiotic treatment with carbenicillin and gentamicin showed a high degree of effectiveness against the micro-organism, the livel of the urinary bacterial count being taken as the parameter for the histopathological changes. Bacterial counts in renal tissue of up to 104 bacteria/ml in histopathological and urinobacteriological residual findings after a 12-day period of treatment indicate the importance of a long-term antibiotic treatment of pyelonephritis.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00554594
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