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  • Electronic Resource  (2)
  • 3-aminopropyltriethoxysilane  (1)
  • Aggression  (1)
  • 1
    ISSN: 1432-2072
    Keywords: Serotonin ; Tryptophan ; Aggression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In order to study the effect of decreasing plasma tryptophan levels on aggressive responding in a controlled laboratory setting, we administered two doses (25 g and 100 g) of a tryptophan-free amino acid mixture to ten healthy male subjects after 24 h of a low tryptophan diet. Subjects were screened for current or past psychiatric, or non-psychiatric medical illness. Aggressive responding on a free-operant laboratory measure of aggression (the Point Subtraction Aggression Paradigm) and plasma tryptophan levels were measured before and after drinking the amino acid mixture. There was a significant increase in aggressive responding 5 h after the 100 g mixture and a significant increase in aggressive responding 6 h after the 25 g mixture compared to a baseline day when no drink was administered. There was also a significant decrease in plasma tryptophan at 5 hours after ingestion compared to baseline for both doses of amino acid mixture. This study supports the hypothesis that tryptophan depletion increases aggressive responding in healthy males in a laboratory setting; probably by decreasing brain serotonin.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of sol gel science and technology 13 (1998), S. 553-558 
    ISSN: 1573-4846
    Keywords: water soluble silica ; colloids ; 3-aminopropyltriethoxysilane ; tetramethoxysilane ; reversible gel ; DLVO theory
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The unique sol/gel behavior of an organic/inorganic hybrid material synthesized from 3-aminopropyl-triethoxysilane (3AS) and tetramethoxysilane (TMOS) is discussed and examined. The addition of H2O to a mixture of a basic (3AS) and an acidic (TMOS) alkoxide leads to rapid gel formation. This wet gel reverses to a sol upon heating which is attributed to the dissolution of siloxane bonds between the surfaces of colloidal particles in the gel. The reversed sol dries to an optically transparent solid which is water soluble. The water solubility and the stability of these colloidal particles are described by their aminopropyl/silanol surface and the electrostatic interactions between them using DLVO theory.
    Type of Medium: Electronic Resource
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