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  • Digitale Medien  (4)
  • Auto-PEEP  (2)
  • Corticosterone methyl oxidase type II  (1)
  • Ductopenia  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Arthrogryposis, renal dysfunction and cholestasis syndrome: Report of five patients from three Italian families (1995)
    Springer
    European journal of pediatrics 154 (1995), S. 835-839 
    Details
    ISSN: 1432-1076
    Schlagwort(e): Neurogenic arthrogryposis ; Parenchymal giant cell transformation ; Pigmentary liver disease ; Ductopenia ; Renal tubulopathy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract We report on five patients from three families with neurogenic arthrogryposis, cholestasis and tubular renal dysfunction. Despite a similar clinical picture the liver histology showed a broad pathological spectrum, ranging from pigment storage to parenchymal giant cell transformation and ductopenia. The findings are compared with those of other cases from the literature in search of a correct nosology of the syndrome characterized by arthrogryposis, renal and liver disease. Conclusion We propose to consider the picture of arthrogryposis, renal tubular dysfunction and cholestasis as a single syndrome.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01959793
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  • 2
    Digitale Medien
    Digitale Medien
    Corticosterone methyl oxidase type II deficiency: a cause of failure to thrive and recurrent dehydration in early infancy (1992)
    Springer
    European journal of pediatrics 151 (1992), S. 170-173 
    Details
    ISSN: 1432-1076
    Schlagwort(e): Corticosterone methyl oxidase type II ; Failure to thrive ; Salt wasting
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Corticosterone methyl oxidase type II (CMO II) deficiency is an uncommon cause of salt-wasting in infancy. We describe a boy who presented with recurrent dehydration and severe failure to thrive in the first 3 months of life, associated with mild hyponatraemia (serum Na+ 127–132 mEq/l) and hyperkalaemia (serum K+ 5.3–5.9 mEq/l). The diagnosis was suggested by an elevated plasma renin activity (PRA): serum aldosterone ratio, and subsequently confirmed by an elevated serum 18-hydroxycorticosterone: aldosterone ratio. Treatment with 9α-fluorohydroxycortisone normalized growth parameters and PRA levels. CMO II deficiency should be considered in infants with recurrent dehydration and failure to thrive, even when serum sodium and potassium levels are not strikingly abnormal.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01954376
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  • 3
    Digitale Medien
    Digitale Medien
    Pressure support ventilation (PSV) reverses hyperinflation induced isorhythmic A-V dissociation (1989)
    Springer
    Intensive care medicine 15 (1989), S. 319-321 
    Details
    ISSN: 1432-1238
    Schlagwort(e): Auto-PEEP ; COPD ; Pressure support ventilation
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract We report a case of hyperinflation induced isorythmic atrio-ventricular dissociation with circulatory failure in a patient with chronic obstructive pulmonary disease. The arrythmia was successfully treated by applying “pressure support ventilation” (PSV: 20 cmH2O) which, by decreasing the respiratory rate and increasing the expiratory time reduced the level of auto-PEEP. In order to explain this result the Authors recorded, in the same patient, the level of auto-PEEP and ΔFRC obtained with Intermittent Positive Pressure Ventilation (IPPV), Intermittent Mandatory Ventilation (IMV) and PSV at the same gas exchange values. PSV showed a dramatic reduction of both these parameters. (Auto-PEEP: IPPV 12 cmH2O, IMV 17 cmH2O, PSV 7 cmH2O).
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00263868
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  • 4
    Digitale Medien
    Digitale Medien
    Auto-PEEP and dynamic hyperinflation in COPD patients during controlled mechanical ventilation and high frequency jet ventilation (1990)
    Springer
    Intensive care medicine 16 (1990), S. 81-84 
    Details
    ISSN: 1432-1238
    Schlagwort(e): COPD ; High frequency jet ventilation ; Auto-PEEP
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract We investigated the levels of auto-PEEP and dynamic hyperinflation during high frequency jet ventilation (HFJV) and controlled mechanical ventilation (CMV) in six patients with chronic obstructive pulmonary disease within the first 36 h of acute exacerbation. The comparative evaluation was performed at similar conditions of gas exchange in HFJV and CMV: PaO2 77.6±11 mmHg vs 80.8±12 mmHg; PaCO2 46.8±2.5 mmHg vs 47±2.8 mmHg; pH 7.38 vs 7.38. In this situation, the values of auto-PEEP and dynamic hyperinflation, expressed as Δ over the apneic functional residual capacity (FRC) did not differ: (auto-PEEPHFJV 8.9±3.8 cmH2O; auto-PEEPCMV 8.8±4.7 cmH2O; ΔFRCHFJV 0.56±0.19 l; ΔFRCCMV 0.54±0.2 l). This result suggests that, with a suitable machine setting and similar gas exchanges, HFJV produces the same level of auto-PEEP and dynamic hyperinflation as CMV in patients with chronic obstructive pulmonary disease.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01699850
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