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  • Electronic Resource  (2)
  • Axonal Degeneration  (1)
  • Distal blood pressure  (1)
  • 1
    ISSN: 1432-0533
    Keywords: Cholinesterase ; Axonal Degeneration ; Polyneuropathy ; Carbon Disulphide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Intramuscular nerves in the anterior tibial muscle of rats with carbon disulphide (CS2)-induced polyneuropathy were studied ultrastructurally and after histochemical demonstration of non-specific cholinesterase (Ns. ChE; E.C.3.1.1.8) activity. After 5 weeks' exposure to CS2 the intramuscular nerves showed occasional weak Ns. ChE activity, which did not appear in the normal intramuscular nerves. Axoplasmic ultrastructure was normal in the majority of the nerves. After 5 months' exposure to CS2 there was intense Ns. ChE activity along intrauscular nerve trunks. The axoplasm of the nerves showed marked degeneration: distended smooth-surfaced vacuoles, dense bodies, disappearance of neurotubules and appearance of increased amounts of neurofilaments. The present findings suggest that histochemical demonstration of Ns. ChE activity can be employed as an indicator of early axonal degeneration in progressive polyneuropathy.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 56 (1987), S. 440-443 
    ISSN: 1439-6327
    Keywords: Vibration syndrome ; Distal blood pressure ; Neurology ; Neurophysiology ; Peripheral nerves
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Twenty three patients with hand-arm vibration exposure and diagnosed vibration syndrome were given a thorough clinical and neurophysiological examination, together with finger strain gauge plethysmography. Eleven of the patients were forest workers regularly using chain saws (low frequency vibration exposure), and twelve were metal grinders (higher frequency vibration exposure). Both groups had significantly lower finger blood pressures than healthy controls, and comparisons between the groups indicated that the mean values tended to be lower in the grinders. The findings suggest that hand-arm vibration exosure is associated with obstructive changes in the distal arteries of the fingers, and that vibration frequency is one of the factors determining the severity of the changes and the time of onset of the symptoms.
    Type of Medium: Electronic Resource
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