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  • Electronic Resource  (3)
  • Cataract  (1)
  • Heterocannibalism  (1)
  • Key words: EHDP — Osteoclast — Apoptosis — Actin rings.  (1)
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  • Electronic Resource  (3)
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  • 1
    Electronic Resource
    Electronic Resource
    Etidronate (EHDP) Inhibits Osteoclastic-Bone Resorption, Promotes Apoptosis and Disrupts Actin Rings in Isolate-Mature Osteoclasts (1999)
    Springer
    Calcified tissue international 64 (1999), S. 219-223 
    Details
    ISSN: 1432-0827
    Keywords: Key words: EHDP — Osteoclast — Apoptosis — Actin rings.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract. Bisphosphonates, therapeutic reagents against tumoral bone diseases (Paget's disease or osteoporosis), are potent inhibitors of bone resorption. The mechanisms by which they directly act on mature osteoclasts remain unclear. Using a recently developed technique for isolation of highly purified mammalian mature osteoclasts, we demonstrated that etidronate [ethane-1-hydroxy-1,1-diphosphonate (EHDP), 1-hydroxy-1,1-ethylidenebisphosphonate], inhibited directly osteoclastic bone-resorbing activity by pit assay. In addition, EHDP also directly induced apoptosis and disrupted actin rings in osteoclasts. The data support previous data on non-purified osteoclasts and results in vivo.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002239900606
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    A case of Menkes syndrome with cataracts (1982)
    Springer
    European journal of pediatrics 138 (1982), S. 357-358 
    Details
    ISSN: 1432-1076
    Keywords: Menkes' syndrome ; Cataract
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 2-year and 9-month-old boy with Menkes syndrome is reported. In addition to the typical features of this syndrome our patient had bilateral cataracts. The relation between abnormal copper metabolism and cataract is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00442519
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Interspecific differences in male cannibalistic behavior between two sympatric cardinalfishes (Pisces: Apogonidae) (2000)
    Springer
    Journal of ethology 18 (2000), S. 5-10 
    Details
    ISSN: 1439-5444
    Keywords: Key words Filial cannibalism ; Heterocannibalism ; Mate availability ; Operational sex ratio ; Paternal mouthbrooder
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Cannibalistic behavior of a paternal mouthbrooding cardinalfish, Apogon notatus, was examined and compared with that of a sympatric congener, Apogon doederleini. In both species, males sometimes cannibalized their own entire broods, but their postcannibalistic behavior was markedly different. Males of A. doederleini respawned within a few days of cannibalism, usually changing mates, whereas males of A. notatus took several weeks to respawn, less frequently changing mates. This difference was attributed to mate availability for males. The operational sex ratio was female biased in A. doederleini but male biased in A. notatus, suggesting that the former males have higher mate availability and thus opportunities for remating soon after cannibalism. For male apogonids that accept only one clutch at a time, an effective way to compensate for reproductive loss entailed by filial cannibalism is to remate as soon as possible after cannibalism. The higher rate of filial cannibalism by A. doederleini than by A. notatus suggests that this cannibalism is facilitated by high mate availability. In contrast to filial cannibalism, heterocannibalism was more frequent in A. notatus. High population density and gregariousness may be important factors contributing to the frequent occurrence of heterocannibalism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s101640070017
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    Paper (German National Licenses)
    Fulltext
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