ISSN:
1432-1076
Keywords:
Delayed puberty
;
Growth rate
;
Growth hormone concentration (mean daily growth hormone concentration)
;
Testosterone concentration (mean daily testosterone concentration)
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The mean growth hormone concentration during a 24-hour period in 7 boys of short familial stature and a growth rate of 3.2–5.4 cm/year was between 1.0 and 4.6 ng/ml serum. In 7 boys with pubertal growth spurt and familial tallness (growth rate 7.2–11.0 cm/year) it varied from 0.97 to 4.4 ng/ml and in 6 boys with constitutional delay of puberty (a growth rate of 4.2–5.2 cm/year prior to puberty) from 1.3 to 4.3 ng/ml. No correlation was found between the 24-hour mean growth hormone concentration and the mean 24-hour testosterone concentration in serum or the growth rate, but a correlation was found between testosterone and the growth rate. It is concluded that the growth spurt in puberty is not due to a change in growth hormone concentration but rather to the increase of androgen production in puberty.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00466266
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