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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Analytical chemistry 24 (1952), S. 182-185 
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Autonomic & autacoid pharmacology 25 (2005), S. 0 
    ISSN: 1474-8673
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Chemistry and Pharmacology , Medicine
    Notes: 1 Microinjection of peptide YY (PYY) (0.23–2.3 nmol) into the posterior hypothalamic nucleus (PHN) of conscious rats evokes a dose-dependent pressor response and a bradycardia. 2 The increase in mean arterial pressure evoked by 2.3 nmol of PYY was not blocked by intravenous pretreatment with: (i) the nicotinic ganglionic receptor antagonist pentolinium (PENT, 10 mg kg−1) alone, or in combination with the muscarinic receptor antagonist methylatropine (MeATR, 1 mg kg−1); (ii) the α1-adrenoceptor antagonist prazosin (PRAZ, 0.2 mg kg−1); (iii) the V1-vasopressin receptor antagonist [d(CH2)5Tyr(Me)]AVP (AVPX, 20 μg kg−1); (iv) the combination of AVPX, PENT and MeATR; (v) the combination of PRAZ, AVPX, PENT, MeATR, and the α2-adrenoceptor antagonist yohimbine (0.3 mg kg−1); or (vi) the angiotensin II type 1 receptor antagonist ZD 7155 (1 mg kg−1). 3 Adrenal demedullation inhibited the PYY-evoked responses of drug-naïve rats, and rats pretreated with the combination of PENT, MeATR and AVPX. 4 Transection of the splanchnic nerve innervating the adrenal medullae attenuated the bradycardia, as did ZD 7155, but not the PYY-evoked pressor response. 5 Systemic pretreatment of rats with the neuropeptide Y1 receptor antagonist BIBP 3226 (1 mg kg−1) blocked the PYY-evoked cardiovascular changes, but not those evoked by microinjection of carbachol (5.5 nmol) into the PHN. 6 These results suggest that the cardiovascular changes evoked from the PHN by PYY requires the presence of the adrenal medullae, which are stimulated by: (i) a hormone to release an NPY-like substance that evokes the pressor response, and (ii) the splanchnic nerve to evoke the release of a substance that results in the bradycardia.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the American Water Resources Association 23 (1987), S. 0 
    ISSN: 1752-1688
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Architecture, Civil Engineering, Surveying , Geography
    Notes: : The current increase in the demand for water by municipal, industrial, and other users is likely to result in approximately one-third less water being available for agricultural use in Texas by the year 2000. As water supplies diminish, the rainfall excess needs to be used more efficiently. Large amounts of runoff occur in the eastern part of Texas that could be collected in small impoundments and utilized for crop production. Farmers in water-surplus basins or subbasins can apply for a permit to divert surface water into small on-farm impoundments to be used for supplemental irrigation. The costs for runoff collection and two supplemental irrigations, which amount to a total of 4 in./yr., are estimated to be approximately $60/acre/year. Depending upon the crop produced, the estimated increase in gross income from supplemental irrigation ranges from about $80 to more than $100 per acre annually.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1365-3091
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: Some of the Earth's largest submarine debris flows are found on the NW African margin. These debris flows are highly efficient, spreading hundreds of cubic kilometres of sediment over a wide area of the continental rise where slopes angles are often 〈1°. However, the processes by which these debris flows achieve such long run-outs, affecting tens of thousands of square kilometres of seafloor, are poorly understood. The Saharan debris flow has a run-out of ≈700 km, making it one of the longest debris flows on Earth. For its distal 450 km, it is underlain by a relatively thin and highly sheared basal volcaniclastic layer, which may have provided the low-friction conditions that enabled its extraordinarily long run-out. Between El Hierro Island and the Hijas Seamount on the continental rise, an ≈25- to 40-km-wide topographic gap is present, through which the Saharan debris flow and turbidites from the continental margin and flanks of the Canary Islands passed. Recently, the first deep-towed sonar images have been obtained, showing dramatic erosional and depositional processes operating within this topographic `gap' or `constriction'. These images show evidence for the passage of the Saharan debris flow and highly erosive turbidity currents, including the largest comet marks reported from the deep ocean. Sonar data and a seismic reflection profile obtained 70 km to the east, upslope of the topographic `gap', indicate that seafloor sediments to a depth of ≈30 m have been eroded by the Saharan debris flow to form the basal volcaniclastic layer. Within the topographic `gap', the Saharan debris flow appears to have been deflected by a low (≈20 m) topographic ridge, whereas turbidity currents predating the debris flow appear to have overtopped the ridge. This evidence suggests that, as turbidity currents passed into the topographic constriction, they experienced flow acceleration and, as a result, became highly erosive. Such observations have implications for the mechanics of long run-out debris flows and turbidity currents elsewhere in the deep sea, in particular how such large-scale flows erode the substrate and interact with seafloor topography.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 34 (1978), S. 2648-2650 
    ISSN: 1600-5740
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Chemical Physics Letters 84 (1981), S. 555-559 
    ISSN: 0009-2614
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 777 (1996), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Notes: The β-amyloid precursor protein (β-APP) has been hypothesized to play an important role in the establishment of synaptic connections. Icv injections of anti-βAPP antibodies into rat brains produced no appreciable effect on subsequent learning of a passive avoidance task whereas memory assessed 1 day later in a retention test was impaired in anti-β-APP– but not control-IgG–injected animals. This suggests a possible involvement of β-APPs in cognitive functions. In order to evaluate the properties of the proteolytic Aβ-fragment accumulating in Alzheimer's disease brains, four different neuronal cell types were exposed to Aβ1–42 for 24 hours. All cells degenerated in response to Aβ, yet chromosomal condensation and internucleosomal DNA fragmentation, typical for apoptosis, occurred in only three of the cell types tested. These findings suggest that β-APPs may play an important role in cognitive processes and additionally, that their alternative proteolytic product Aβ may be differentially toxic to neuronal cell types, inducing cell death either by necrosis or by apoptosis.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 38 (1982), S. 105-106 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Male rats were subjected to sham surgery or total abdominal vagotomy and then subsequently received a chronic i.v. cannula. Vagotomy attenuated the dipsogenic effects of infusions of hypertonic saline and sucrose that were observed in the control rats.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 35 (1979), S. 1270-1272 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary An inexpensive drinkometer system is described that is compatible with most data acquisition systems and can be used for continuously monitoring the drinking pattern of laboratory animals. The change in electrical inductance resulting from the descent of a free-floating ferrite unit through a drinking tube, surrounded by a double coil, is converted to a signal proportional to the volume of fluid consumed.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 38 (1982), S. 814-814 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Following surgical construction of a chronic end-to-side portacaval shunt, rats consumed more 6% ethanol than their controls in a schedule-induced polydipsia paradigm during the baseline condition and during intermittent food delivery. Blood enthanol was higher in rats with portacaval shunts than in controls following the final test session.
    Type of Medium: Electronic Resource
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