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  • Electronic Resource  (4)
  • Engineering  (2)
  • Glioma  (1)
  • Meningioma  (1)
  • 1
    ISSN: 1432-2307
    Keywords: Arachnoid villi ; Meningioma ; Glutathione S-transferase placental type ; Cerebrospinal fluid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Human normal dura mater containing arachnoid villi were examined for their expression of glutathione S-transferase placental type (GST-π), a detoxifying enzyme, using an immunohistochemical method. All of the arachnoid villi and arachnoid cells in five normal cases were found to have expression of GST-π, although no positive reaction for the enzyme was present in other tissues of the dura mater. The results show a possible role for arachnoid tissues in protecting human brain from hazardous xenobiotics in the cerebrospinal fluid. Twenty-six meningiomas were also examined for expression of the enzyme. Tissues of meningotheliomatous meningiomas were always positive for expression of the enzyme. Transitional meningiomas also showed the expression in their meningotheliomatous components. No staining reaction of GST-π was recognized in fibroblastic meningiomas except for two cases with a tendency to meningotheliomatous differentiation. The findings suggest a functional similarity between the arachnoid tissues and meningotheliomatous components of meningiomas.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0942-0940
    Keywords: Glioma ; metastatic brain tumour ; Ki-67 ; nucleolar organizer regions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Sixteen cases of malignant brain tumours comprising 6 anaplastic astrocytomas, 3 glioblastoma multiforme, 1 medulloblastoma and 6 metastatic brain tumours were investigated independently by a silver colloid method for nucleolar organizer regions (NORs) and an immunohistochemistry using a monoclonal antibody against a nuclear antigen, Ki-67, in proliferating cells. The correlation between the mean number of NORs and the percentage of Ki-67 labelled cells (Ki-67 labelling index) was examined. In addition, four normal brain tissue samples without neoplastic cells were stained for NOR. The mean number of NORs in these malignant brain tumours was significantly greater than that in normal astrocytes (p〈0.001). Moreover, both the mean number of NORs and the Ki-67 labelling index in metastatic brain tumours were significantly greater than those in high-grade gliomas (p〈0.001). The Ki-67 labelling index and the mean number of NORs in malignant brain tumours including metastatic brain tumours were found to be linearly related (r=0.86). These results suggest that the proliferative potential of malignant brain tumours could be evaluated by NOR score as well as Ki-67 labelling index and that such indices provide clear discrimination between high-grade gliomas and metastatic brain tumours.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 20 (1984), S. 2175-2195 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A finite element method for contact problems in crack mechanics is developed on the basis of the penalty function method. The method is successfully applied to three important problems in fracture mechanics: a crack propagated from a pin hole, a two-point supported specimen with an edge crack loaded by a stamp, and a thick plate with a through-wall crack under bending force.
    Additional Material: 24 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 11 (1977), S. 604-605 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Type of Medium: Electronic Resource
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